BackgroundMany Canadian population health studies, including those focusing on the relationship between exposure to air pollution and health, have operationalized neighbourhoods at the census tract scale. At the same time, the conceptualization of place at the local scale is one of the weakest theoretical aspects in health geography. The modifiable areal unit problem (MAUP) raises issues when census tracts are used as neighbourhood proxies, and no other alternate spatial structure is used for sensitivity analysis. In the literature, conclusions on the relationship between NO2 and health outcomes are divided, and this situation may in part be due to the selection of an inappropriate spatial structure for analysis. Here, we undertake an analysis of NO2 and respiratory health in Ottawa, Canada using three different spatial structures in order to elucidate the effects that the spatial unit of analysis can have on analytical results.ResultsUsing three different spatial structures to examine and quantify the relationship between NO2 and respiratory morbidity, we offer three main conclusions: 1) exploratory spatial analytical methods can serve as an indication of the potential effect of the MAUP; 2) OLS regression results differ significantly using different spatial representations, and this could be a contributing factor to the lack of consensus in studies that focus on the relation between NO2 and respiratory health at the area-level; and 3) the use of three spatial representations confirms no measured effect of NO2 exposure on respiratory health in Ottawa.ConclusionsArea units used in population health studies should be delineated so as to represent the a priori scale of the expected scale interaction between neighbourhood processes and health. A thorough understanding of the role of the MAUP in the study of the relationship between NO2 and respiratory health is necessary for research into disease pathways based on statistical models, and for decision-makers to assess the scale at which interventions will have maximum benefit. In general, more research on the role of spatial representation in health studies is needed.

A land use regression (LUR) model for the mapping of NO2 concentrations in Ottawa, Canada was created based on data from 29 passive air quality samplers from the City of Ottawa’s National Capital Air Quality Mapping Project and two permanent stations. Model sensitivity was assessed against three spatial representations of population: population at the dissemination area level, population at the dissemination block level and a dasymetrically derived population representation. A spatial database with land use, roads, population, zoning, greenspaces and elevation was created. Polycategorical zoning data were used in dasymetric mapping to spatially focus population data derived from the dissemination blocks to a sub-block level for comparison purposes. Dasymetric population mapping provided no significant LUR model improvement in explained variance when compared to block level population; however, both the former were significantly better than the dissemination area level population representations. However, where block level population is not available or too costly to acquire, our method using polycategorical zoning data provides a viable alternative in LUR modelling endeavours.

No abstract

No abstract

No abstract