[1] The mean vertical structure of mesoscale eddies in the Peru-Chile Current System is investigated by combining the historical records of Argo float profiles and satellite altimetry data. A composite average of 420 (526) profiles acquired by Argo floats that surfaced into cyclonic (anticyclonic) mesoscale eddies allowed constructing the mean three-dimensional eddy structure of the eastern South Pacific Ocean. Key differences in their thermohaline vertical structure were revealed. The core of cyclonic eddies (CEs) is centered at ∼150 m depth within the 25.2-26.0 kg m −3 potential density layer corresponding to the thermocline. In contrast, the core of the anticyclonic eddies (AEs) is located below the thermocline at ∼400 m depth impacting the 26.0-26.8 kg m −3 density layer. This difference was attributed to the mechanisms involved in the eddy formation. While intrathermocline CEs would be formed by instabilities of the surface equatorward coastal currents, the subthermocline AEs are likely to be shed by the subsurface poleward Peru-Chile Undercurrent. In the eddy core, maximum temperature and salinity anomalies are of ±1°C and ±0
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