Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.
genesis of COVID-19 infection, isotretinoin should be utilized at low dose with proper care of the nasal mucosa.Isotretinoin is an oral retinoid approved for the management of severe cases of acne vulgaris, and recently utilized for mild to moderate acne. 2 COVID-19, is a respiratory disease caused by the SARS-CoV-2 virus and it was stated a pandemic on 11 March 2020. Advanced age
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