The growing interest in environmental issues and increasing demands to develop materials that do not burden the natural environment significantly are currently observed. In this connection many studies on polymer degradation in different environments are carried out. It is important to consider the influence of synergistic action of various factors in order to understand the environmental degradation of synthetic polymers. This requires understanding of interactions between polymer and living organisms. This paper reviews current authors research on environmental degradation of polyurethanes.The comparison of environmental degradability of polyurethanes in the "altic Sea water and compost under natural weather depending conditions is presented. The environmental degradation of poly ester-urethane based on poly ethylene-butyleneadipate and poly ester-urethane based on poly ε -caprolactone was evaluated.The characteristic parameters of sea water temperature, pH, salt, and oxygen contents and of compost temperature, pH, moisture content, and activity of