Objectives: To investigate the role of individual's taste sensitivity using 6-n-propylthiouracil (PROP) in the development of white spot lesions (WSLs) in adolescent orthodontic patients. Materials and Methods: 44 healthy adolescents, aged 12 to 16 years old, who were in fixed-appliance orthodontic treatment for at least 6 months, consented to participate in this cross-sectional study. Data regarding participants' demographic information, oral hygiene practices, and dietary habits were obtained by a questionnaire. An oral clinical examination was performed to determine the oral hygiene status, the presence of WSLs and dental caries experience. The taste phenotype of the participants was evaluated through PROP test and they were accordingly divided into PROP nontasters and PROP tasters. Results: The sample consisted of 24 subjects in the WSL group and 20 subjects in the WSL-free group. The WSL group demonstrated higher mean plaque score (48.2), mean decayed, missing, and filled surfaces (2.38), and mean decayed, missing, and filled teeth (1.96) scores compared to the WSL-free group (38.7, 0.85, and 0.55, respectively), but no significant differences were found. Most subjects in the WSL group were PROP nontasters (66.6%) whereas most subjects in the WSL-free group were PROP tasters (75%); a significant difference was observed between the groups (P = .006). Conclusions: The prevalence of white spot lesions was significantly higher in adolescent orthodontic patients who were PROP nontasters compared to PROP tasters. A PROP taste perception could be a potential risk factor for the formation of WSLs during fixed orthodontic treatment that warrants further attention.

Aim: The aim of this case report is to discuss the features of molar incisor hypomineralization (MIH), a developmental enamel defect, which was noted in a set of monozygotic twin males. Summary: MIH is the hypomineralization of one to four first permanent molars (FPMs) frequently associated with affected incisors and varies in clinical severity. Early diagnosis and management of the condition is paramount and will avoid the premature loss of the molars. Key learning points: The clinical characteristics, as well as the short and long term management of this condition are discussed.

An 18.3 year old female, R.S, with a diagnosis of Williams syndrome presented herself to the European University College mobile screening van Aim: The aim of this case report is to describe the medical and dental features of an 18 year old female diagnosed with Williams syndrome (WS). Summary: Williams syndrome is a rare, genetically determined multisystem disorder involving the cardiovascular system, musculoskeletal system, dysmorphic facies, intellectual disabilities and dental anomalies. Key learning points: The short term and long term dental management of patients with Williams syndrome is discussed.