The term "Wolf's isotopic response" describes the occurrence of a new skin disorder
at the site of another unrelated and already healed skin disease. In most cases,
herpes zoster is the inicial disease. Different disorders may develop on the same
site, most commonly granulomatous and lichenoid reactions, infiltration of
hematologic diseases, skin tumors and infections. There are few related cases of
lichen planus presenting as isotopic response. We report a case of a 74 year-old
woman, with multiple itchy, rose-colored and shiny papules that developed at site of
previously healed herpes zoster, on the right arm and shoulder. The pathogenesis of
this phenomenon is still unknown and further studies are needed.
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