<abstract> <p>Drug nanocarriers have been continuously improved to promote satisfactory release control. In this sense, luminescent materials have become an alternative option in clinical trials due to their ability to monitor drug delivery. Among the nanocarriers, silica stands out for structural stability, dispersibility, and surface reactivity. When using ceramic nanocarriers, one of the challenges is their interaction and selectivity capability for organic molecules, such as drugs. In order to overcome such adversity, superficial modifications can be carried out to enable a higher affinity for the desired drug. Thus, the present study aimed to obtain silica nanoparticles (NPs) doped with low concentrations of europium (III) superficially modified by (3-aminopropyl)triethoxysilane (APTES) to assess their interaction with the model drug cloxacillin benzathine. This drug was chosen because it is part of the ampicillin family and is commonly used in several treatments. Near-spherical and homogeneous silica NPs were obtained via sol-gel synthesis, with particle sizes of approximately 21 nm. It was possible to verify the fluorescence capacity of the silica NPs when doped with europium (III) in a mole percent that varied from 0.5 to 3.0%. A 10% volume percent of APTES caused the silica nanoparticles to increase the degree of hydrophobicity, with a shift in the contact angle from 8° to 51°. After surface modification by APTES, the silica nanocarrier (10 g·L<sup>-1</sup>) achieved a satisfactory degree of CLOX incorporation (25 g·L<sup>-1</sup>), increasing the adsorptive capacity to values above 50%. Therefore, silica NPs doped with europium (III) in a low percent of 0.5% (mole) modified by APTES showed promising results as an alternative option for trials and clinical studies of drug incorporation.</p> </abstract>
Starch materials are subject to loss of initial characteristics due to the retrogradation degenerative effect, high hygroscopicity, and favoring the growth of the microorganisms, which reduces the shelf life of packaging. In this sense, the insertion of nanoparticulated CuO was evaluated for the best performance.CuO is a semiconductor that can improve optical, mechanical, and antimicrobial properties, enabling excellent promotion of starch films. The hot injection precipitation method was used to obtain CuO nanoparticles in the nanometric scale rapidly. The films were carried out from the starch homogenization in water and urea under temperature, followed by thermopressing at 120 C. As a result, the 1% CuO (w w À1 ) increased tensile strength from 0.87 ± 0.40 to 1.92 ± 0.09 MPa. Furthermore, the films containing nanoparticles showed a barrier property against radiation in the ultraviolet-visible spectrum, not observed for the micrometric scale. Such results were attributed to the superior opacity of the films generated by nanometric reinforcement. Concerning antimicrobial activity, the films containing CuO showed a fungistatic effect (33%) for the Alternaria alternata fungus, a microorganism very susceptible to carbohydrate-rich sources. Thus, the CuO-reinforced starch films improved physicochemical and biological properties, making them promissory candidates for commercial application.
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Magnetic nanoparticles are a promising alternative as a support in adsorption processes, aiming at the easy recovery of the aqueous medium. A faujasite zeolite (FAU) surface was decorated with magnesium ferrite (MgFe2O4) nanoparticles. FAU is a porous adsorbent with high specific surface area (SSA) and chemical stability. The FAU:MgFe2O4 nanocomposite 3:1 ratio (w w−1) promotes the combination of the surface and magnetic properties. The results showed the effectiveness of the MgFe2O4 immobilization on the FAU surface, exhibiting a high SSA of 400 m2 g−1. The saturation magnetization (Ms) was verified as 5.9 emu g−1 for MgFe2O4 and 0.47 emu g−1 for FAU:MgFe2O4, an environmentally friendly system with soft magnetic characteristics. The magnetic nanocomposite achieved high adsorption values of around 94% removal for Co2+ and Mn2+ ions. Regarding its reuse, the nanocomposite preserved adsorption activity of above 65% until the third cycle. Thus, the FAU:MgFe2O4 nanocomposite presented favorable adsorptive, magnetic, and recovery properties for reuse cycles in polluted water.
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