Background Clinical features and outcomes of SARS-CoV-2 infections diverge in different countries. The aim of this study was to describe clinical characteristics and outcomes in a cohort of patients hospitalized with SARS-CoV-2 in Argentina. Methods Multicenter prospective cohort study of ≥18 years-old patients with confirmed SARS-CoV-2 infection consecutively admitted to 19 hospitals in Argentina. Multivariable logistic regression models were used to identify variables associated with 30-day mortality and admission to intensive care unit (ICU). Results A total of 809 patients were analyzed. Median age was 53 years, 56% were males and 71% had at least one comorbidity. The most common comorbidities were hypertension (32%), obesity (23%) and diabetes (17%). Disease severity at admission was classified as mild 25%, moderate 51%, severe 17%, and critical 7%. Almost half of patients (49%) required supplemental oxygen, 18% ICU, and 12% invasive ventilation. Overall, 30-day mortality was 11%. Factors independently associated with ICU admission were male gender (OR 1.81; 95%CI 1.16–2.81), hypertension (OR 3.21; 95%CI 2.08–4.95), obesity (OR 2.38; 95%CI 1.51–3.7), oxygen saturation ≤93% (OR 6.45; 95%CI 4.20–9.92) and lymphopenia (OR 3.21; 95%CI 2.08–4.95). Factors independently associated with 30-day mortality included age ≥60 years-old (OR 2.68; 95% CI 1.63–4.43), oxygen saturation ≤93% (OR 3.19; 95%CI 1.97–5.16) and lymphopenia (OR 2.65; 95%CI 1.64–4.27). Conclusions This cohort validates crucial clinical data on patients hospitalized with SARS-CoV-2 in Argentina.

Background: In the context of a worldwide syphilis increment, the worst scenario is during pregnancy: if the correct treatment is not realized on time, the conception's product will be affected, amplifying this infection dimension.General Objective: Determine why pregnant women with syphilis did not receive the correct therapy.Specific Objectives: Determine absolute and relative frequency of pregnant women without treatment, inadequate one, or with reinfections, and their reasons.Stablish conception products (abortion, stillbirth, newborn) frequencies and describe the lastone's clinical situation.Methods & Materials: Methodology: observational retrospective study, based on clinical files revision.Period: Between January 1st 2015 and September 30th 2017 Inclusion Criteria: Pregnant women who finalize pregnancy in our hospital with acute syphilis.Results: During the study, 224 gestational syphilis were diagnosed, 165(73%) had the delivery in our hospital, hence were included in the study.Seroprevalence among pregnant women in our hospital during 2015 and 2016 was 1.27% and 2.24% respectively. The median age each year was 24 years in 2015 and 22 in 2016 and 2017 (p: 0.164). 76 (46%) out of 165 gestational syphilis included did not receive treatment, or it was inadequate, hence their children were assumed as congenital syphilis: 66 as suspicious (20 dead fetuses or abortion) and 10 as confirmed. The reasons why this situation could not be avoided are described below: