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The cellulose is the most widely distributed skeletal polysaccharide and represents about 50% of the cell wall material of plants. Beside hemicellulose and lignin, cellulose is a major component of agricultural wastes and municipal residues. The cellulose and hemicellulose comprise the major part of all green plants and this is the main reason of using such terms as "cellulosic wastes" or simply "cellulosics" for those materials which are produced especially as agricultural crop residues, fruit and vegetable wastes from industrial processing, and other solid wastes from canned food and drinks industries. The cellulose biodegradation using fungal cells is essentially based on the complex interaction between biotic factors, such as the morphogenesis and physiology of fungi, as the cellulose composition and its complexness with hemicellulose and lignin (Andrews & Fonta, 1988; Carlile & Watkinson, 1996). An efficient method to convert cellulose materials, in order to produce unconventional highcalorie foods or feeds, is the direct conversion by cellulolytic microorganisms. Theoretically, any microorganism that can grow as pure culture on cellulose substrata, used as carbon and energy sources, should be considered a potential organism for "single-cell protein" (SCP) or "protein rich feed" (PRF) producing. 2. Biotechnology of mycelia biomass producing through submerged bioconversion of agricultural crop wastes The submerged cultivation of mushroom mycelia is a promising method which can be used in novel biotechnological processes for obtaining pharmaceutical substances of anticancer,

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