Phosphorylation
Phosphorylation O 0278Cyclophosphorylation of Polyphenols by Diamidoarylphosphites. -The phosphorylation of polyphenols with aromatic diamidophosphites proceeds by an anomalous pathway via rupture of only one P-N bond and one P-O bond, whereas the second P-N bond remains intact. In the reaction of bisphenols (VII) with phosphite (VIII) [and also with (II)], intermediates like (IX) are isolated which under higher reaction temperatures undergo cyclization to give dioxaphosphocines (X). It is supposed that the unusual lack of reactivity of the second P-N bond is due to the spatial arrangement of this amido group with respect to the reaction site in phosphorylated intermediates such as (IX). -(MASLENNIKOVA, V. I.; MERKULOV, R. V.; DYAGILEVA, M. V.; VASYANINA, L. K.; LYSSENKO, K. A.; ANTIPIN, M. Y.; WEBER, D.; BAUER, I.; HABICHER, W. D.; NIFANTYEV*, E. E.; Tetrahedron 59 (2003) 10,
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