In this paper we are approaching, from a computational perspective, the problem of promoter sequences prediction, an important problem within the field of bioinformatics. As the conditions for a DNA sequence to function as a promoter are not known, machine learning based classification models are still developed to approach the problem of promoter identification in the DNA. We are proposing a classification model based on relational association rules mining. Relational association rules are a particular type of association rules and describe numerical orderings between attributes that commonly occur over a data set. Our classifier is based on the discovery of relational association rules for predicting if a DNA sequence contains or not a promoter region. An experimental evaluation of the proposed model and comparison with similar existing approaches is provided. The obtained results show that our classifier overperforms the existing techniques for identifying promoter sequences, confirming the potential of our proposal.
This paper details a number of indoor localization techniques developed for real-time monitoring of older adults. These were developed within the framework of the i-Light research project that was funded by the European Union. The project targeted the development and initial evaluation of a configurable and cost-effective cyber-physical system for monitoring the safety of older adults who are living in their own homes. Localization hardware consists of a number of custom-developed devices that replace existing luminaires. In addition to lighting capabilities, they measure the strength of a Bluetooth Low Energy signal emitted by a wearable device on the user. Readings are recorded in real time and sent to a software server for analysis. We present a comparative evaluation of the accuracy achieved by several server-side algorithms, including Kalman filtering, a look-back heuristic as well as a neural networkbased approach. It is known that approaches based on measuring signal strength are sensitive to the placement of walls, construction materials used, the presence of doors as well as existing furniture. As such, we evaluate the proposed approaches in two separate locations having distinct building characteristics. We show that the proposed techniques improve the accuracy of localization. As the final step, we evaluate our results against comparable existing approaches.
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