The type of cytokines present in the semen will depend on the single or simultaneous presence of leukocytes and/or pathogens. Chronic male genital tract infections could be associated with the development of anti-HSP-60 antibodies and anti-sperm antibodies.

Cómo citar este artículo: Cucunubá ZM, et al. Primer consenso colombiano sobre Chagas congénito y orientación clínica a mujeres en edad fértil con diagnóstico de Chagas. Infectio. 2014. http://dx.

Palabras clave: transfusión sanguínea, hepatitis B, bancos de sangre. Colombia. Absence of occult hepatitis B in Colombian blood donorsIntroduction. In Colombian blood banks, screening for the surface antigen of hepatitis B is mandatory in all units collected. Testing of antibody against core antigens is not administered, although this method may be useful to detect donors infected with the hepatitis B virus. Objective. The prevalence of occult hepatitis B was determined by applying a full-serological profile of hepatitis B virus to blood samples of blood donors. Materials and methods. Between April 2008 and October 2009, a prospective cross sectional study was conducted using 628 samples from donors to blood banks located in four Colombian cities. Prevalence for hepatitis B had been previously recorded for these cities. Serological screening was performed for the complete virus; then nucleic acid amplification was tested in sera that were anti-HBc reactive and with a titer of anti-HBs ≤30 mUI/ml. Results. Of the 628 samples tested, 129 met the serological criteria established to be tested nucleic acid amplification. None of them demonstrated evidence of nucleic acid amplification of hepatitis B virus. Conclusions. This is the first study in Colombia to detect the presence of blood donors that may be occult hepatitis B carriers. None was detected.

Introducción. La enfermedad de Chagas es un problema de salud pública en Latinoamérica. Después de la vectorial, la segunda fuente de transmisión es la transfusional; en Colombia el tamizaje para este marcador es obligatorio en los bancos de sangre desde 1995. Objetivo. Evaluar el comportamiento de algunas estrategias de control de la infección en donantes y estimar el riesgo transfusional por enfermedad de Chagas. Materiales y métodos. Se analizaron los datos de cobertura de tamizaje y reactividad para anticuerpos anti-Trypanosoma cruzi; los resultados de los bancos de sangre en el Programa de Evaluación Externa del Desempeño de Serología (PEED) y los reportes de los Laboratorios de Salud Pública sobre pruebas confirmatorias de serología en donantes. Resultados. En 2003, los bancos de sangre del país captaron 482.371 unidades, 99,91% fueron analizadas para anti-T.cruzi, resultando reactivas 0,42%. Casanare presentó la mayor reactividad con 107/1.487 (7,2%), de los cuales se confirmaron como positivos 75. En el PEED participaron 45,5% bancos, la totalidad de los cuales utilizó ELISA para tamizaje; se hallaron 1,1% resultados falsos positivos y ningún falso negativo. En 12 departamentos que analizaron 338.563 unidades para anti-T.cruzi, 1.298 casos fueron notificados como reactivos y 1.108 (85,4%) se confirmaron por la prueba de IFI, registrando una positividad de 0,33%. Conclusiones. Aunque la cobertura del tamizaje llegó a 99,91%, existe aún riesgo de infección por T.cruzi. Los casos de T.cruzi en donantes oscilan entre 0 y 50 por cada mil, y como ya se mencionó, Casanare es el departamento con mayor riesgo de adquirir Chagas transfusional. Los bancos participantes en el PEED no mostraron resultados falsos negativos.Palabras clave: bancos de sangre, Trypanosoma cruzi, enfermedad de Chagas, Colombia, control de calidad. Control of infection for the Trypanosoma cruzi in blood donorsIntroduction. Chagas disease is a public health problem in Latin America. Whereas the primary source of transmission is the insect vector, the second is by blood transfusion. Consequently, in Colombia, screening for trypanosomiasis has been obligatory for blood donors since 1995. Objective. The effectiveness ot current strategies for infection control in donors was evaluated in order to estimate the risk of blood stock contamination with Chagas disease. The screening data came from the blood banks in the Program of External Evaluation in the Performance of Serology and the reports of the Laboratories of Public Health on confirming donor serology tests. Results. In 2003, 482,371 units of blood were collected in all of Colombia Of these, 99.9% were analyzed for anti-T.cruzi reactivity, with a positives of 0.42% detected. The Casanare Province presented the biggest number of reactive donors 107/1,487 (7.2%), with 75 confirmed positive. In the Program of External Evaluation in the Performance of Serology, 45.5% of all banks participated-all used ELISA for screening of anti-T.cruzi. 1.1% false positives and nofalse negatives were indicated ...

Characterize the confirmed cases of T. cruzi and identify their current location through the looking for the information and its comparation with the national data bases is an important sources to find these confirmed cases in order to give a relevant clinical procedure by the competent authorities.