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In this paper, some important properties, from the application point of view, of mango (Mangifera indica) almond fat var. Manila (MAF) were analyzed by differential scanning calorimetry and X-ray diffraction techniques. The thermal profile, the solid fat content (SFC) and the predominant polymorphism of MAF samples, previously characterized chemically, were studied. The results showed that this fat, from one of the main residues of mango industrialization, had a relatively simple fusion/crystallization behavior. Stabilized samples showed a simple SFC profile with one marked slope between 35 and 40 7C. Different thermal histories demonstrated the existence of at least four polymorphs. The non-stabilized samples corresponded predominantly to the formation of the crystalline a form. The stabilized samples, tested under several time and temperature conditions, allowed the formation of two other polymorphs, which are both unstable forms and were formed during a to b polymorphic transition. The X-ray diffraction information confirmed the presence of the less and more stable MAF polymorphs, allowing us to conclude that MAF is a b-stable fat, just as is cocoa butter.

Activity-guided investigation of crude extracts prepared from the root bark of Picramnia antidesma, a medicinal plant long used for the treatment of malaria in tropical areas of the Americas, when tested on KB cells led to the isolation of a new compound, 10-epi-uveoside, from a cytotoxic fraction containing a rich mixture of anthrone glycosides. The antiplasmodial activity proved to be a result of the high levels of cytotoxicity displayed by the anthraquinone derivatives and therefore infusions from this crude drug lack the selectivity index needed to be an effective antimalarial agent.

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