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Saponins are plant-derived non-ionic surfactants and widely applied in many products, such as cosmetics, cleansers, medicines, vaccine, as additives by therapeutic properties and chemical characteristics theirs. These substances are of growing interest for drug research as they’re active constituents of several folk medicines, in addition to comprising an important class of medicinal chemistry. Triterpenoid saponins are secondary metabolites, these’re largely distributed in plant species and they’re characterized as one of the active principles of these. These saponins have potent anti-viral, adjuvant, hemolytic, cytotoxic and anti-angiogenic activities that are relationship with the presence of characteristics chemical moiety. In this work was summarized the studies found in the scientific literature on the therapeutic properties of triterpenoid saponins, as well as commercial applicability theirs. Recent works have suggested some triterpenoid saponins like candidates for treatment of patients with COVID-19.

Saponinas esteroidais são uma importante classe de metabólidos secundários, estas são amplamente distribuídas em muitas espécies de plantas e são caracterizadas como princípio ativos destes produtos naturais. Saponinas tem sido investigadas ao longo dos anos, devido as suas potentes propriedades terapêuticas. Neste trabalho foram resumidos os estudos encontrados na literatura científica acerca das investigações das atividades biológicas e caracterização estrutural de saponinas esteroidais. Estudos recentes tem sugerido algumas saponinas como candidatas ao tratamento de pacientes com a doença do Coronavirus (COVID-19).