Cystic fibrosis is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene. This disorder produces a variable phenotype including lung disease, pancreatic insufficiency, and meconium ileus plus bilateral agenesis of the vas deferens causing obstructive azoospermia and male infertility. Preimplantation genetic diagnosis is an alternative that allows identification of embryos affected by this or other genetic diseases. We report a case of couple with cystic fibrosis; the woman had the I148 T mutation and the man had the Delta F508 gene mutation. The couple underwent in vitro fertilization, associated with preimplantation genetic diagnosis, and with subsequent selection of healthy embryos for uterine transfer. The result was an uneventful pregnancy and delivery of a healthy male baby.
En ce beau jour, d´anniversaire Ô mon aimée, ma tendre mére Dois je te dire que l´amour Que j´ai pour toi, la nuit, le jour N´est que simple reconnaissance De la bonté, la benifaisance De l´embassable dévouement Que chaque jour, à tout moment Tu m´as toujours donné la preuve, Dans la vie et parfois l´epreuve, Me soutenant de ton amour Sans jamais défailler un jour Je t´adore ô ma chére mére De cela tu ne dois douter Ta Cristina, aimant fille Jamais ne pourra oublier Tes témoignages de tendresse Et la douceur de tes caresses Lorsque elle était petite enfant Et qu´elle aimé toujours autant De bien loin, ma chére mére, Reçois mille baisers bien doux En attendant le jour De me retourner prés de vous Tu voudras bien les partager Avec ma tante bien aimé Que j´aime bien fort elle aussi. v À minha mãe Hérmínia, com muita saudade. À minha tia Lucrécia, pelas emoções não compartilhadas.
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