Background and Objectives: Stroke is a leading cause of long-term disability. Rehabilitation involving repetitive, high-intensity, and task-specific exercise is the pathway to restore motor skills. Robotic assistive devices such as Gloreha are increasingly being used in upper limb rehabilitation. The aim of this study is to explore the efficacy of robotic therapy for upper limb rehabilitation using robotic glove (Gloreha) in patients with stroke. Materials and Methods: The patients affected by stroke who were admitted to our rehabilitation unit were studied. Patients were exposed to Gloreha device rehabilitation (30 min/die), physiotherapy (1,5 hours/die), and occupational therapy (30 min/die). We measured the impairment in motor function and muscle tone using the modified Ashworth scale (MAS), the activities of daily living functional independence measure (FIM), and the finger dexterity Nine-Hole Peg test (NHPT). Results: Twelve patients (mean age = 64.5 years; male/female: 8:4) were admitted at the rehabilitation training. We found statistically significant differences between admission and discharged in terms of functional recovery using the FIM scale (pre/M = 88.33; post/M = 117.25, P = 0.01); hand training showed a better outcome using the NHPT (pre/M = 51.8; post/M = 36.33, P = 0.01). No significant changes were observed in terms of spasticity with the MAS (pre/M = 1.25; post/M = 1.08;P > 0.05). Conclusions: Rehabilitation with robotic glove (Gloreha) can positively promote functional recovery of arm function in a patient with stroke.

Background and Objectives: In neurorehabilitation, exoskeleton plays a key role among the numerous innovative and advanced frontiers in technology. The exoskeleton is intended for rehabilitation and mobility in patients with neurological motor diseases. The aim of this study is to evaluate the impact of robotic training in body perception and mood. Methods: Two patients, one affected by stroke and another affected by spinal cord injury admitted to our rehabilitation unit, have been studied. We used two exoskeletons (Ekso and Indego). Training occurred 3 days a week for a total of forty sessions, with a duration of 50-60 min each session. Psychological tests focused on depression (Beck Depression Inventory), self-perception (body uneasiness test A), and the workload (NASA-Task Load Index) were used. Results: After the treatment, we found a great improvement in mood disorders and body perception in the patients. Conclusions: Patients with neurological motor diseases can increase motor and psychological skills using an active powered exoskeleton.

The prefrontal cortex (PFC) has extensive reciprocal connections with nearly all cortical and subcortical structures, placing it in a unique position to orchestrate a wide range of cognitive and affective neural functions. Damage of PFC in humans is associated with profound changes in social and affective behavior. The development of new technologies in the field of cognitive rehabilitation is giving us the opportunity to use computer-based cognitive tools to improve the recovery of patients affected by acquired brain injury.