AimsTo compare the gait of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) patients with healthy controls, using a machine-learning approach.Patients and Methods145 participants (121 healthy controls, 12 patients with cruciate-retaining TKA, and 12 with mobile-bearing medial UKA) were recruited. The TKA and UKA patients were a minimum of 12 months post-operative, and matched for pattern and severity of arthrosis, age, and body mass index. Participants walked on an instrumented treadmill until their maximum walking speed was reached. Temporospatial gait parameters, and vertical ground reaction force data, were captured at each speed. Oxford knee scores (OKS) were also collected. An ensemble of trees algorithm was used to analyse the data: 27 gait variables were used to train classification trees for each speed, with a binary output prediction of whether these variables were derived from a UKA or TKA patient. Healthy control gait data was then tested by the decision trees at each speed and a final classification (UKA or TKA) reached for each subject in a majority voting manner over all gait cycles and speeds. Top walking speed was also recorded.Results92% of the healthy controls were classified by the decision tree as a UKA, 5% as a TKA, and 3% were unclassified. There was no significant difference in OKS between the UKA and TKA patients (p = 0.077). Top walking speed in TKA patients (1.6 m/s; 1.3 to 2.1) was significantly lower than that of both the UKA group (2.2 m/s; 1.8 to 2.7) and healthy controls (2.2 m/s; 1.5 to 2.7; p < 0.001). ConclusionUKA results in a more physiological gait compared with TKA, and a higher top walking speed. This difference in function was not detected by the OKS.Cite this article: Bone Joint J 2016;98-B(10 Suppl B):16–21.

This survey focuses on two challenging speech processing topics, namely: speaker segmentation and speaker clustering. Speaker segmentation aims at finding speaker change points in an audio stream, whereas speaker clustering aims at grouping speech segments based on speaker characteristics. Model-based, metric-based, and hybrid speaker segmentation algorithms are reviewed. Concerning speaker clustering, deterministic and probabilistic algorithms are examined. A comparative assessment of the reviewed algorithms is undertaken, the algorithm advantages and disadvantages are indicated, insight to the algorithms is offered, and deductions as well as recommendations are given. Rich transcription and movie analysis are candidate applications that benefit from combined speaker segmentation and clustering.

Highlights• An algorithmic method that detects knee osteoarthritis.• Machine learning, specifically random forests, is applied on ground reaction forces.• Discriminating parameters of knee osteoarthritis are automatically detected.• Parameters have a clinical interpretation and are in line with medical literature.• The proposed approach is subject-independent.

An algorithm for automatic speaker segmentation based on the Bayesian Information Criterion (BIC) is presented. BIC tests are not performed for every window shift (e.g. every milliseconds), as previously, but when a speaker change is most probable to occur. This is done by estimating the next probable change point thanks to a model of utterance durations. It is found that the inverse Gaussian fits best the distribution of utterance durations. As a result, less BIC tests are needed, making the proposed system less computationally demanding in time and memory, and considerably more efficient with respect to missed speaker change points. A feature selection algorithm based on branch and bound search strategy is applied in order to identify the most efficient features for speaker segmentation. Furthermore, a new theoretical formulation of BIC is derived by applying centering and simultaneous diagonalization. This formulation is considerably more computationally efficient than the standard BIC, when the covariance matrices are estimated by other estimators than the usual maximum likelihood ones. Two commonly used pairs of figures of merit are employed and their relationship is established. Computational efficiency is achieved through the speaker utterance modeling, whereas robustness is achieved by feature selection and application of BIC tests at appropriately selected time instants. Experimental results indicate that the proposed modifications yield a superior performance compared to existing approaches.

Abstract-This paper addresses unsupervised speaker change detection, a necessary step for several indexing tasks. We assume that there is no prior knowledge either on the number of speakers or their identities. Features included in the MPEG-7 Audio Prototype are investigated such as the AudioWaveformEnvelope and the AudioSpecrtumCentroid. The model selection criterion is the Bayesian Information Criterion (BIC). A multiple pass algorithm is proposed. It uses a dynamic thresholding for scalar features and a fusion scheme so as to refine the segmentation results. It also models every speaker by a multivariate Gaussian probability density function and whenever new information is available, the respective model is updated. The experiments are carried out on a dataset created by concatenating speakers from the TIMIT database, that is referred to as the TIMIT data set. It is and demonstrated that the performance of the proposed multiple pass algorithm is better than that of other approaches.

In this paper, a class of algorithms for automatic classification of individual musical instrument sounds is presented. Several perceptual features used in sound classification applications as well as MPEG-7 descriptors were measured for 300 sound recordings consisting of 6 different musical instrument classes. Subsets of the feature set are selected using branchand-bound search, obtaining the most suitable features for classification. A class of classifiers is developed based on the non-negative matrix factorization (NMF). The standard NMF method is examined as well as its modifications: the local, the sparse, and the discriminant NMF. The experimental results compare feature subsets of varying sizes alongside the various NMF algorithms. It has been found that a subset containing the mean and the variance of the first mel-frequency cepstral coefficient and the AudioSpectrumFlatness descriptor along with the means of the AudioSpectrumEnvelope and the AudioSpectrumSpread descriptors when is fed to a standard NMF classifier yields an accuracy exceeding 95%.

This study proposes a framework for deconstructing complex walking patterns to create a simple principal component space before checking whether the projection to this space is suitable for identifying changes from the normality. We focus on knee osteoarthritis, the most common knee joint disease and the second leading cause of disability. Knee osteoarthritis affects over 250 million people worldwide. The motivation for projecting the highly dimensional movements to a lower dimensional and simpler space is our belief that motor behaviour can be understood by identifying a simplicity via projection to a low principal component space, which may reflect upon the underlying mechanism. To study this, we recruited 180 subjects, 47 of which reported that they had knee osteoarthritis. They were asked to walk several times along a walkway equipped with two force plates that capture their ground reaction forces along 3 axes, namely vertical, anterior-posterior, and medio-lateral, at 1000 Hz. Data when the subject does not clearly strike the force plate were excluded, leaving 1–3 gait cycles per subject. To examine the complexity of human walking, we applied dimensionality reduction via Probabilistic Principal Component Analysis. The first principal component explains 34% of the variance in the data, whereas over 80% of the variance is explained by 8 principal components or more. This proves the complexity of the underlying structure of the ground reaction forces. To examine if our musculoskeletal system generates movements that are distinguishable between normal and pathological subjects in a low dimensional principal component space, we applied a Bayes classifier. For the tested cross-validated, subject-independent experimental protocol, the classification accuracy equals 82.62%. Also, a novel complexity measure is proposed, which can be used as an objective index to facilitate clinical decision making. This measure proves that knee osteoarthritis subjects exhibit more variability in the two-dimensional principal component space.

This paper addresses the problem of unsupervised speaker change detection. Three systems based on the Bayesian Information Criterion (BIC) are tested. The first system investigates the AudioSpectrumCentroid and the AudioWaveformEnvelope features, implements a dynamic thresholding followed by a fusion scheme, and finally applies BIC. The second method is a real-time one that uses a metric-based approach employing the line spectral pairs and the BIC to validate a potential speaker change point. The third method consists of three modules. In the first module, a measure based on second-order statistics is used; in the second module, the Euclidean distance and T 2 Hotelling statistic are applied; and in the third module, the BIC is utilized. The experiments are carried out on a dataset created by concatenating speakers from the TIMIT database, that is referred to as the TIMIT data set. A comparison between the performance of the three systems is made based on t-statistics.