poses a significant risk. For example, a survey of complications associated with yellow fever immunization showed that 4 out of 23 vaccinees who developed vaccineassociated viscerotropic disease had an underlying thymoma (and, we presume, Good's syndrome). 5 Most thymomas are slow growing with a tendency to recur locally; they seldom metastasize and can usually be cured by surgical resection. 6 Primary intrapulmonary thymoma without an associated mediastinal component, as seen here, is exceptionally rare. 7 These tumours arise from ectopic embryonic tissue. As far as we are aware, this is the first reported case of hypogammaglobulinaemia associated with such a tumour. REFERENCES 1 Engels EA, Pfeiffer RM. Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies.
poses a significant risk. For example, a survey of complications associated with yellow fever immunization showed that 4 out of 23 vaccinees who developed vaccineassociated viscerotropic disease had an underlying thymoma (and, we presume, Good's syndrome). 5 Most thymomas are slow growing with a tendency to recur locally; they seldom metastasize and can usually be cured by surgical resection. 6 Primary intrapulmonary thymoma without an associated mediastinal component, as seen here, is exceptionally rare. 7 These tumours arise from ectopic embryonic tissue. As far as we are aware, this is the first reported case of hypogammaglobulinaemia associated with such a tumour. REFERENCES 1 Engels EA, Pfeiffer RM. Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies.
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