OBJECTIVE-Few studies have quantified the prevalence of weight-related orthopedic conditions in otherwise healthy overweight children. The goal of the present investigation was to describe the musculoskeletal consequences of pediatric overweight in a large pediatric cohort of children that included severely overweight children.METHODS-Medical charts from 227 overweight and 128 nonoverweight children and adolescents who were enrolled in pediatric clinical studies at the National Institutes of Health from 1996 to 2004 were reviewed to record pertinent orthopedic medical history and musculoskeletal complaints. Questionnaire data from 183 enrollees (146 overweight) documented difficulties with mobility. In 250, lower extremity alignment was determined by bilateral metaphyseal-diaphyseal and anatomic tibiofemoral angle measurements made from whole-body dual-energy x-ray absorptiometry scans. RESULTS-Comparedwith nonoverweight children, overweight children reported a greater prevalence of fractures and musculoskeletal discomfort. The most common self-reported joint complaint among those who were questioned directly was knee pain (21.4% overweight vs 16.7% nonoverweight). Overweight children reported greater impairment in mobility than did nonoverweight children (mobility score: 17.0 ± 6.8 vs 11.6 ± 2.8). Both metaphyseal-diaphyseal and anatomic tibiofemoral angle measurements showed greater malalignment in overweight compared with nonoverweight children.CONCLUSIONS-Reported fractures, musculoskeletal discomfort, impaired mobility, and lower extremity malalignment are more prevalent in overweight than nonoverweight children and adolescents. Because they affect the likelihood that children will engage in physical activity, orthopedic difficulties may be part of the cycle that perpetuates the accumulation of excess weight in children. Orthopedic complications of excess weight in adults include progression of degenerative osteoarthritis and articular cartilage breakdown, 4,5 a decline in physical functioning, 6 and poorer outcomes after orthopedic surgery for obesity-related disorders. 7,8 Some orthopedic disorders that are unique to childhood also have been suggested to be weight related. For example, retrospective analyses of children and adolescents with slipped capital femoral epiphysis and adolescent tibia vara (Blount's disease) reveal overrepresentation of overweight individuals. 9-11 However, few prospective data that quantify the prevalence and manifestations of potentially weight-related orthopedic conditions in overweight children and adolescents who are not referred for orthopedic concerns are available. Furthermore, the impact of such conditions on mobility in overweight children has not previously been examined. KeywordsThe goal of the present investigation was to describe the musculoskeletal consequences of pediatric overweight in a large cohort of children who ranged in BMI from normal to severely overweight. We hypothesized that, compared with nonoverweight children and adolescents, those who were...

Overweight, treatment-seeking adolescents with BED are clearly distinguishable from teens without the disorder on measures of eating-related psychopathology, mood, and anxiety. RECENT-BINGE, but not PAST-LOC, is also associated with significantly greater eating-related and general psychopathology.

The ability to consume large quantities of palatable foods, coupled with decreased subsequent satiety, may play a role in the greater weight gain found in binge-eating children.