Microphotometrical scanning and computer graphic image analysis were carried out to detect the distribution of chromatin densities in subtelomeric segments of T-banded endoreduplicated chromosomes of Chinese hamster ovary (CHO) cells. Chromatin density patterns detected with this method were similar to those previously found in CHO and normal human chromosomes. The highest chromatin densities were considered as marker segments which led to the detection of reciprocal changes of position in endoreduplicated chromosomes during cell spreading on the slide. The problem of the subtelomeric T-banding density patterns found in the endoreduplicated chromosomes and their relation to the structure and molecular composition of this region is briefly discussed. Empregaram-se técnicas de escaneamento microfotométrico e análise de imagem gráfica computadorizada para detectar a distribuição de densidades de cromatina em segmentos subteloméricos de cromossomos endo-reduplicados com bandeamento T de células do ovário do hamster chinês (CHO). Os padrões de densidade de cromatina detectados com este método foram similares aos previamente encontrados em CHO e cromossomos humanos normais. As densidades de cromatina mais elevadas foram consideradas como segmentos marcadores que levaram à detecção de alterações recíprocas de posição de cromossomos endo-reduplicados durante o espalhamento das células na lâmina. O problema dos padrões de densidade de bandeamento T subteloméricos encontrados nos cromossomos endo-reduplicados e sua relação com a estrutura e a composição molecular desta região é discutido brevemente
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