The location of a puncture needle’s tip and the resistance of tissue against puncture are crucial information for clinicians during a percutaneous procedure. The tip location and needle alignment can be observed by image guidance. Tactile information caused by tissue resistance to rupture, allow clinicians the perception of structural changes during puncture. Nevertheless, this sense is individual and subjective. To improve percutaneous procedures, the implementation of transducers to enhance or complement the senses offer objective feedback to the user. Known approaches are e.g. based on integrated force sensors. However, this is connected to higher device costs, sterilization and certification issues. A recent publication shows the implementation of an audio transducer clipped at the proximal end of the needle. This sensor is capable of acquiring emitted sounds of the distal tiptissue interaction that are transmitted over the needle structure. The interpretation of the measured audio signals is highly depended on the transmission over the needle, the tissue and, the penetration depth. To evaluate the influence of these parameters, this work implements a simplified experimental setup in a controlled environment with a minimum of noise and without micro tremors induced by clinician’s hands. A steel rod simulating a needle is inserted into pork meat of different thickness. A controlled impact covering the needle’s tip mimics tissue contact. The resulting signals are recorded and analyzed for better understanding of the system.
IntroductionContrast media injections, infusions, or experiments that require a constant volume flow close to or within a very high magnetic field like in magnetic resonance imaging (MRI) require a liquid reservoir and a power unit to deliver the fluid. However, most power units are driven by motors that are either not MRI-compatible or require external connections that restrict mobility and usage. In this paper, the development of a highly portable, lightweight, and MRI-compatible pump system is explained.MethodsThe energy required to deliver the flow is generated using a pressurized bottle concept. The valve inside the bottle is opened to create a flow which should be maintained constant. In order to find the optimal flow resistance for a constant flow rate, we created multiple setups with different flow resistance.ResultsWe measured the flow rates for different flow resistances by attaching a restring valve to the bottle. The results clearly show that high flow resistance results in lower and more constant flow rate.DiscussionThe optimal flow rate achieved using our current setup was significantly constant but not ideal. Consequently, such a pump system can be used in many medical applications like MRI-compatible contrast agent injectors.
Background: The magnetic resonance imaging (MRI) environment with its high-strength magnetic fields requires specialized and sometimes sophisticated solutions for otherwise simple problems. One of these problems is MR-compatible actuator mechanisms that transfer a signal into an action. Purpose: Normal actuators are based on a magnetic effect (eg, relays) and will typically not work in magnetic fields exceeding 1000 G, eg, inside the bore of an MR scanner. To enable the use of clinical devices inside the MRI, eg, for interventional procedures, there is a need for fully compatible actuators. Patients and methods: Various actuators were compared for the purpose as a simple onoff switch within an MRI. NITNOL wire as an actuator showed the highest potential because of its simplicity and reliability. We tested the possible force achieved by the NITINOL wire related to the respective energy consumption, to provide a travel range of 2 mm. Results: Compared to other actuators, the NITNOL wire is cheaper and requires less space. In the switching process however, there is a delay due to the time required for the heating of the wire up to the transformation temperature. The NITINOL switch shows a reliable behavior with regard to the generated force and the switching path over the entire measurement. Significant artifacts, caused by the NITNOL wire could not be detected in the MRI. Conclusion: NITINOL wires can be repeatedly used, are relatively easy to implement and could be an economic alternative to other more complicated actuator technologies.
Phantoms mimicking special physiological processes of the human body are essential for evaluating prototypes of medical devices. Especially for thermometric MRI measurements, the temperature distribution in the brain needs to be simulated. Since this parameter is dependent on the tissue perfusion, a new hydrogel by MAGDASSIS et al. was evaluated in this work for building models with hollow artery structures. This hydrogel can be polymerized through UV-light due to the nanoparticles contained in it. Additionally, thermal parameters were measured and compared to human brain tissue. The indirect manufacturing of hydrogel phantoms showed good qualitative results for vessels with a diameter > 3 mm. In this process a 3D printed wax core was inserted in the hydrogel and the structure was then UV cured after molding. After curing the core was dissolved in an isopropanol bath. The thermal properties, obtained by the transient planesource- method, showed similar values compared to that of human brain tissue mentioned in literature. Further limitations in the manufacturing process needs to be overcome to use the indirect manufacture approach for smaller vessels of the brain.
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