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Association with 1927 nm thulium laser was able to amplify the effectiveness of PDT and to promote tissue remodeling. Despite the positive response to our case, clinical studies are lacking and further analysis could be performed on a wider population to better define correct dosage and safety profile. Further, it is necessary to compare this procedure with other treatments to establish the real effectiveness.

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Multiple areas in the cerebral cortex are active during the listening of narrative material, and these activations in the brain produce significant changes in connectivity. In a pathological population living in nursing homes, patients who underwent daily narrative training showed some improvements in many psychological and cognitive aspects.Here we aim to investigate the effects of such training in many cognitive aspects. At the beginning and end of a 40-day narrative training, participants with cognitive decline were tested with the Repeatable Battery for the Assessment of Neuropsychological Status to quantify any improvements in individual performance. Results were compared with those of a control group of patients. Results show a significant increase in performances of the experimental group in domains such as immediate memory, language, attention, and delayed memory. Results replicate and expand previous findings, indicating that this type of training could increase cognitive performance and could be implemented as an effective nonpharmacological treatment for the cognitive wellness in both the pathological and nonpathological elderly.

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Many areas in the cortex are active during reading of narrative material, and these activations in the brain produce significant changes in connectivity. Following previous results showing cognitive benefits in memory domains of a narrative training program in nursing home patients living with dementia, the aim of the present study was to perform a more in depth investigation of the effects of this training on memory domains and other cognitive areas. Methods: An experimental group of eight patients underwent auditory narrative training of 60 hours. At the beginning and end of the training, subjects were tested with a neuropsychological battery to quantify any improvements in individual performance. Results: The results showed a statistically significant improvement in the list learning task (immediate memory) and list learning recognition for single tasks, and a statistically significant improvement in overall cognitive area scores for immediate and delayed memory. Conclusion: Results replicate and expand our previous findings, indicating that this type of intervention can increase performance on memory-related tests.

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