Among the general ICU subjects receiving mechanical ventilation, use of an MI-E device during respiratory physiotherapy resulted in a larger amount of airway mucus clearance than respiratory physiotherapy alone. (ClinicalTrials.gov registration NCT03178565.).

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Background Although there are simple and low-cost measures to prevent healthcare-associated infections (HAI), they remain a major public health problem. Quality issues and a lack of knowledge about HAI control among healthcare professionals may contribute to this scenario. Aim To present the implementation of a project to prevent HAI in intensive care units (ICU) using the quality improvement (QI) collaborative model Breakthrough Series (BTS). Methods A QI report was conducted to assess the results of a national project in Brazil between January/2018 and February/2020. A one-year pre-intervention analysis was conducted to determine the incidence density baseline of the three main HAI: central line-associated bloodstream infections (CLABSI), ventilation-associated pneumonia (VAP), and catheter-associated urinary tract infections (CA-UTI). The BTS methodology was applied during the intervention period to coach and empower healthcare professionals providing evidence-based, structured, systematic, and auditable methodologies and QI tools to improve patients’ care outcomes. Results A total of 116 ICUs were included in this study. The three HAI showed a significant decrease of 43.5%, 52.1%, and 65.8% for CLABSI, VAP, and CA-UTI, respectively. A total of 5,140 infections were prevented. Adherence to bundles inversely correlated with the HAI incidence densities: CLABSI insertion and maintenance bundle (R = -0.50, P-value = 0.010 and R = -0.85, P-value <0.001, respectively), VAP prevention bundle (R = -0.69, P-value <0.001), and CA-UTI insertion and maintenance bundle (R = -0.82, P-value <0.001 and R = -0.54, P-value = 0.004, respectively). Conclusion Descriptive data from the evaluation of this project show that the BTS methodology is a feasible and promising approach to preventing HAI in critical care settings.

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Objetivo: descrever perfil e desfechos clínicos de pacientes diagnosticados com COVID-19 admitidos em hospital privado na região Sul do Brasil. Método: estudo descritivo, realizado com 110 pacientes com COVID-19 que necessitaram de internação hospitalar entre março e maio de 2020. Foram coletados dados sociodemográficos, perfil clínico, sinais e sintomas e desfechos clínicos. Adotou-se análise descritiva para interpretação dos dados. Resultados: predominou sexo masculino (64,5%). Comorbidade prevalente: Hipertensão Arterial Sistêmica (45,5%). Sinais e sintomas com maior destaque: tosse (53,6%) e dispneia (48,2%). Desfechos clínicos evidenciados: tomografia de tórax com opacidades em vidro fosco (98,2%), suplementação com oxigenoterapia (86,4%), encaminhamento para Unidade de Internação (90,9%). Intercorrências observadas: arritmias cardíacas (18,2%) e hipoxemia (18,2%). Desfecho final predominante foi alta melhorada (90%). Conclusão: a descrição de perfil e desfecho clínico de pacientes com COVID-19 proporcionará o direcionamento de cuidados com fluxos e protocolos assistenciais que garantam qualidade da assistência e segurança na prática clínica.Descritores: COVID-19. Pacientes. Hospitalização. Pandemias. Enfermagem.Objective: to describe the clinical profile and outcomes of patients diagnosed with COVID-19 admitted to a private hospital in southern Brazil. Method: descriptive study, conducted with 110 patients with COVID-19 who required hospitalization between March and May 2020. Sociodemographic data, clinical profile, signs and symptoms,

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