Background: Cardiovascular disease is one of the chronic diseases with an increasing prevalence from year to year. The results of Indonesia's basic health research (RISKESDAS 2018) showed that it was experienced by 2.9% of the population. Ensuring the continuity of drug availability is very important in pharmacy services for this patient group. The history of drug use is considered in the planning dan procurement of drug products. Objective: This study aims to analyze the drug use pattern and cost of drugs for cardiology outpatients in the National Health Insurance scheme (JKN). Methods: A retrospective observational study was conducted using the prescription of cardiology outpatients JKN for March-May 2021. The ABC method carried out the analysis of drug use patterns and cost. Results: From 2,986 prescriptions for cardiovascular disease, there were 94 types of drugs from 37 therapeutic classes. In the ABC analysis of drug use for class A, 68.82% contained seven types of drugs, class B, 20.55% contained nine types of drugs, and class C, 10.63% with 78 types of drugs. The results of ABC analysis for investment value (cost) of drugs class A 66.96% contained two types of drugs, class B 19.81% with four types of drugs, and class C 14.23% with 88 types of drugs. Conclusion: ABC analysis of the drug use pattern and cost/investment showed different patterns which had value to consider in procurement planning to maintain service continuity.
Penderita kanker dengan modalitas terapi kanker dapat mengalami efek samping obat dan luka kanker. Penyelesaian permasalahan dan peningkatan faktor keselamatan pasien terkait penggunaan obat, serta kualitas hidup yang membaik dipengaruhi oleh kerjasama antara tenaga kesehatan, salah satunya tenaga kesehatan farmasi. Pengetahuan tenaga kefarmasian terkait pengobatan dan perawatan yang diberikan pada pasien kanker sangat dibutuhkan untuk menunjang praktek kolaborasi. Tingkat pengetahuan tenaga kefarmasian penting diketahui untuk upaya penguatan sistem pelayanan kesehatan. Penelitian ini bertujuan untuk mengetahui pengetahuan tenaga kesehatan farmasi terhadap terapi dan rawat luka pasien kanker. Penelitian ini adalah penelitian deskriptif, non-random sampling dengan metode accidental sampling. Penelitian dilakukan pada bulan November 2020, pengumpulan data menggunakan survei online. Total 99 orang tenaga kefarmasian yang terdiri dari apoteker dan tenaga teknis kefarmasian mengisi kuesioner tersebut. Selanjutnya dilakukan penilaian pengetahuan pada setiap butir pertanyaan. Sejumlah 71,72% tenaga kefarmasian memiliki pengetahuan yang baik terhadap hal umum terkait terapi dan rawat luka kanker. Lebih dari sembilan puluh persen tenaga kefarmasian dapat menjawab dengan tepat terkait tujuan terapi kanker, penanggulangan efek samping obat, dan keadaan yang diperhatikan saat perawatan luka. Apoteker memiliki pengetahuan yang baik sebesar 74,39% dan tenaga teknis kefarmasian sebesar 58,82%. Tenaga kefarmasian memiliki pengetahuan yang baik terkait perihal dasar terapi kanker dan rawat luka pasien kanker. Apoteker memiliki pengetahuan yang baik terutama perihal efek samping obat dibandingkan tenaga teknis kefarmasian.
Background: Patients with cardiovascular diseases (CVD) are vulnerable to experiencing drug-drug interactions (DDIs). DDIs are a concern among patients receiving multiple drug regimens but they are also an avoidable cause of adverse drug reactions. The study of potential DDIs (pDDIs) would make it easier for the healthcare provider to deliver better patient care and mitigate pDDIs incidence. Objective: This study aimed to assess the frequency, severity level and risk factors associated with pDDIs among medications used to treat hypertensive ambulatory patients in Universitas Airlangga hospital. Methods: A retrospective observational study was carried out from electronic prescriptions received by hypertensive patients in March 2021. Data collection includes demographic data, the profile of antihypertensive drug use, and pDDIs. pDDIs were identified by severity using Lexicomp Drug Interaction Checker (Application). Univariate logistic regression analysis was used to find associated factors of major pDDIs. A p-value less than 0.05 (≤ 0.05) was considered statistically significant. Results: From 704 patients, 53.98% women and 46.02% men, 89.06% (n = 627) patients had minor to major pDDIs; 1354 pDDIs were identified, 89.4% (n = 1,210) were moderate and 9.8% (n = 133) were major class. Multiple antihypertensive drug regimens had significance associated with the major pDDIs occurrence. Conclusion: We found a high prevalence of pDDIs among hypertensive patients. The majority of pDDIs were of moderate severity. Multiple antihypertensive drug regimens were associated factors in the presence of major pDDIs.
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