A anemia falciforme é uma doença sanguínea genética caracterizada por uma mutação no gene da hemoglobina, gerando uma molécula anormal de hemoglobina (HbS). Esta forma irregular dificulta sua passagem pela rede sangüínea, resultando em crise dolorosa, cansaço e falta de apetite. Algumas vezes as células anormais bloqueiam o fluxo de sangue aos tecidos e órgãos, gerando dor, caracterizando as crises falcêmicas. Esta dor pode sertão intensa ao ponto de levar ao internamento do paciente. Devido à presença de vasos sangüíneos em todas as partes do corpo as lesões podem acontecer em qualquer local. A proposta deste trabalho é abordar as principais manifestações gerais e bucais encontrados em indivíduos portadores da doença.
Sickle cell anemia is a genetic blood disease characterized by a mutation in the hemoglobin gene, creating an abnormal molecule of hemoglobin. This irregular form makes it difficult to pass by the blood net, resulting in a painful crisis, fatigue and appetite lack. Sometimes the abnormal cells block the blood flow to the tissues and organs, causing pain, characterizing the sickle cell crisis. This pain could be so intense that the patient can be hospitalized. Due to presence of the blood vessels in the all body the injuries can happened in any part. The proposal of this article is to show the main general and oral manifestations founded in carriers of sickle cell anemia.
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