Infectious intracranial aneurysms (IIAs) are rare complications of infectious diseases, such as endocarditis and meningitis, caused by the release of bacterial or fungal emboli to the intracranial circulation. The infective emboli can reach the vessel through the endovascular space, as in endocardial infections, or through the extravascular space by contiguous dissemination, in the case of meningitis. Since these emboli tend to be small, they usually reach the distal circulation, causing inflammation in the media and adventitia. This leads to weakening of the vessel wall and aneurysm formation. IIAs account for only 0.7 to 5.4% of all intracranial aneurysms but are still accountable for high lethality 1 . Previous studies describe that hemorrhages due to IIA rupture can reach a mortality rate of 80% and lead to a poor neurologic prognosis 2 . For this reason, early diagnosis and treatment are essential. Unruptured IIA initial management requires long courses of antibiotic treatment. If the control angiogram shows an enlargement of the lesion, surgical resection is indicated. In the case of ruptured IIAs, the treatment consists of surgical excision 3 . The localization of IIAs during surgical procedures is usually difficult since they are small, frequently affects distal branches and can be associated with subarachnoid hemorrhage or intracerebral hematomas 4 . Frameless stereotactic navigation has become a valuable operative adjunct device in recent years 5 , but reports of neuronavigation use for intracranial vascular surgery are scarce in the literature. We have encountered a small number of reports confirming the effectiveness of frameless navigation for atypical aneurysms and brain arteriovenous malformations surgeries 2,5 . We describe the utilization of a frameless stereotactic navigation system for the microsurgical resection of a distal infectious aneurysm. caseThis 34 year-old right handed man was referred to our institution after antibiotic treatment for infectious endocarditis in the two previous weeks. He had a history of rheumatic fever with incomplete treatment in infancy. Transesophageal echocardiography had shown a 3cm vegetation in the anterior leaflet of the mitral valve. Blood cultures had identified Streptococcus viridans as the etiologic agent.Headaches and transient aphasia during the admission motivated a computed tomography (CT) scan that showed a small left frontal hypodense lesion in the middle cerebral artery (MCA) territory distribution, suggesting a previous ischemic event. Cerebral digital angiography was indicated and showed a 2.5 mm saccular aneurysm in the cortical segment of the MCA. After the administration of culture guided antibiotics, a second control angiography was performed and revealed an increase in aneurysm volume, this time measuring 4.1 mm (Fig 1A).The patient was admitted in our institution for surgical treatment and informed consent was obtained. MRI scan with appropriate protocol for neuronavigation was done and demonstrated, on the FLAIR sequence, a small round hy...

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Aiming at the simple neural network's lack of the ability to capture the contextual semantics of text and extract meaningful information in the text, a sentiment analysis model FAGB iAGRU is a fusion of attention mechanism and gated recurrent unit (GRU), is designed. First, the text is preprocessed, and passed GloVe carries out word vectorisation to reduce the dimension of the vector space; then, the attention mechanism is merged with the update gate of the gating unit to form a hybrid model so that it can extract meaningful information in the text features; finally, by forcing forward attention The mechanism further removes text features, and then classifies them by the softmax classifier. Experiments on public data sets show that the algorithm can effectively improve the performance of sentiment analysis. K E Y W O R D Sbelief networks, client-server systems, contracts, data models, data privacy, data protectionThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Contribution: Considering the rapidity of the emergence of new technologies in the modern world, it is necessary to identify and describe potential educational innovations and technologies used as tools for improving healthcare students anatomy learning in the last years. The key contribution of this study is to indicate implementation and other challenges to be overcome. Background: Extensive research demonstrated that several different innovative methods have been used for anatomy teaching. Based on these findings, discussing the most recent existing technologies may be worthwhile. Research Questions: What innovative technologies are being used as tools for improving healthcare students Anatomy learning? What are the main challenges and perspectives related to them? Methodology: This review discussed studies published from 2019 to 2021 found in Embase, IEEE Digital Library, Pubmed, ScienceDirect and Web of Science. Inclusion and exclusion criteria were established and a quality assessment was conducted aiming to mitigate biases and systematic errors. Findings: The databases electronic search identified 149 references and only 10 studies met the minimum cutoff score and were discussed. Compared to traditional methods, alternative learning technologies are excellent ways to improve and transform the education in the health’ system, making it more efficient, economic, practical and accessible.

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grande potencial para substituição do diesel de petróleo. A produção comercial de biodiesel é mais comumente realizada por reação de transesterificação de óleos vegetais ou animais, utilizando catalisadores básicos em condições homogêneas de catálise. No entanto, este processo de produção apresenta algumas desvantagens, tais como: formação de sabão e significativa geração de efluentes. Uma alternativa para simplificar as etapas de purificação do biodiesel, minimizar custos e efluentes é a utilização de catalisadores sólidos que podem ser removidos facilmente do processo produtivo, regenerados e reutilizados. Portanto, este trabalho apresenta um estudo sobre a produção de biodiesel por meio da transesterificação de óleo de soja com metanol, usando óxido misto CaO-CeO 2 como catalisador básico sólido. O catalisador foi obtido por co-precipitação e caracterizado por difração de raios-X. A reação foi conduzida num reator batelada, à 64° C, com razão molar metanol/óleo 20:1. O perfil cinético obtido apresenta forma sigmoidal, obtendo-se rendimento de 85,8 % em 10 h de reação. Este resultado evidencia a possibilidade de utilização de CaO-CeO 2, na produção de biodiesel. Otimização das variáveis de processo e estudos de reuso deste catalisador devem ser estudados para que seu uso comercial seja viabilizado.Palavras-Chave: biodiesel, transesterificação, catálise heterogênea. INTRODUÇÃOO biodiesel, conhecido também como éster metílico de ácidos graxos (FAME), é uma mistura de ésteres monoalquílicos de ácidos graxos de cadeia longa, derivados de matérias-primas renováveis lipídicas, tais como gorduras de óleo vegetal e animal. Considerando o fato do biodiesel possuir propriedades físicas semelhantes aos combustíveis diesel, muitos países ao redor do mundo têm explorado e usado biodiesel comercialmente, misturado ao diesel de petróleo, como EUA, Japão, Brasil, Índia, dentre outros (Janaun e Ellis, 2010).A produção convencional de biodiesel se dá por transesterificação, podendo ser catalisada por meio de processos homogêneos , heterogêneos ou enzimáticos, bem como pela tecnologia supercrítica (Marchetti et al., 2007).

ResumoA indústria têxtil tem buscado inovar em seus produtos e processos, como o uso de biotecnologia -entre essas inovações estão o tratamento enzimático, o tratamento biológico e os demais tratamentos (por exemplo, o "bioblasting"), com destaque para os tratamentos enzimáticos com amilases, celulases, catalases, peroxidases e pectinase. Com o objetivo de avaliar a capacidade inovativa das tecnologias envolvidas nesse cenário, foram utilizados os dados dos documentos patentários extraídos da base INPI-BR, do qual foram selecionados 39 documentos de patentes, sendo 38 relacionados à biotecnologia na indústria têxtil depositados até 2013; 24 sobre tratamento enzimático; quatro sobre tratamento biológico; e 10 sobre demais tratamentos. A evolução temporal revelou um pico entre 1996 e 2000, exceto 1999. Verificou-se que os documentos patentários que tiveram sua família originada no escritório americano (USPTO) tiveram mais relevância nos depósitos patentários com foco no tratamento enzimático, no tratamento biológico e nos demais tratamentos.Palavras-chave: Têxtil. Biotecnologia. Documentos Patentários. Mapeamento Tecnológico. Inovação. AbstractThe textile industry has sought to innovate in its products and processes, such as the use of biotechnology -among them, enzymatic treatment, biological treatment and other treatments (for example bioblasting), highlighting the enzymatic treatment with amylases, cellulases, catalases, peroxidases and pectinase. In order to evaluate the innovative capacity of the technologies involved in this scenario, the data of the patent documents extracted from the INPI-BR database were used, where 39 patent documents were related, 38 of them related to biotechnology in the textile industry deposited by 2013, of which 24 were enzymatic treatment, 4 on biological treatment and 10 on other treatments. The time evolution showed a peak between 1996 and 2000 (except 1999). It was found that the patent documents that had their family originated in the USPTO office had more relevance in the patent deposits with focus on enzymatic treatment, other treatments and biological treatment.Direito autoral e licença de uso: Este artigo está licenciado sob uma Licença Creative atribua a autoria da obra, forneça um link para a licença, e indicar se foram feitas alterações.