In a compliant veteran population, control of blood pressure appeared inadequate but was significantly more likely in those receiving at least three antihypertensive agents. Long-term therapy with simvastatin was independently associated with increased odds of control.
Key Points
Question
Does 48 weeks of pulsed low-intensity ultrasonography (PLIUS) provide therapeutic benefit for patients with idiopathic knee osteoarthritis?
Findings
In this randomized clinical trial of 132 adults with symptomatic and radiographic idiopathic knee osteoarthritis, no statistically significant difference was found between PLIUS and sham therapies for clinical symptoms or tibiofemoral cartilage thickness, the coprimary outcomes.
Meaning
PLIUS as applied in this trial was not effective in ameliorating symptoms or slowing cartilage loss associated with idiopathic knee osteoarthritis.
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