Introduction: Chitin and pectin are important natural polymers which are used as natural catalyst for synthesis of tri- and tetra- phenyl substituted 1H-imidazoles. Material and methods: The reaction of benzil and aromatic aldehydes with ammonium acetate in the presence of chitin produces 2,4,5-triphenyl-1H-imidazoles and the reaction of benzil, aromatic aldehydes and aniline derivatives with ammonium acetate in the presence of pectin produces 1,2,4,5-tetraphenyl-1H-imidazoles, respectively. Results: The results show that synthesis of 2,4,5-triphenyl-1H-imidazoles and 1,2,4,5-tetraphenyl-1H-imidazoles can be catalyzed by chitin and pectin in an effective route, respectively. All synthesized compounds are in good agreement with previously reported compounds. Conclusion: In conclusion, an efficient methodology has been carried out to generate 2,4,5-triphenyl-1H-imidazoles and 1,2,4,5-tetraphenyl-1H-imidazoles, by using non-toxic, cheap and in available catalysis (chitin and pectin).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.