Lasers in dentistry began to gain popularity in the 1990s. Lasers in dentistry are used as a treatment tool or as an adjunct tool. By using the laser in the field of dentistry, the main goal is to overcome the disadvantages, which are currently being experienced in conventional dental treatment procedures. Many specialties in dentistry including oral surgery, implants, oral medicine, periodontics, pediatrics, and operative use the current new laser technology. The ability of lasers to provide minimally invasive procedures with less discomfort to the patient has been useful in the patient delivery system in dental practice. This article describes in brief on the uses of lasers in oral mucosal lesions.