SARS-CoV-2 is the cause of COVID-19. Since the outbreak and rapid spread of COVID-19, it has been apparent that the disease is having multi-organ system involvement. Still its effect in the endocrine system is not fully clear and data on cortisol dynamics in patients with COVID-19 are not yet available. SARS-CoV-2 can knock down the host’s cortisol stress response. Here we present a case of a 51-year-old man vomiting for 10 days after having confirmed COVID-19 infection. He had hypotension and significant hyponatraemia. Work-up was done including adrenocorticotropic hormone stimulation test. He was diagnosed as suffering from adrenal insufficiency and started on steroids with subsequent improvement in both blood pressure and sodium level. COVID-19 can cause adrenal insufficiency. Clinicians must be vigilant about the possibility of an underlying relative cortisol deficiency in patients with COVID-19.
Non-typhoidal salmonella (NTS) is most commonly associated with self-limiting enterocolitis. However, in extremes of age and immune compromised patients, it can cause invasive and disseminated infection, including bacteremia and localized extraintestinal infections. Pneumonia and vertebral osteomyelitis are rare manifestation of NTS, with only a few cases reported worldwide. Our case describes a young man with sickle cell anemia, who developed multifocal invasive NTS infection with pulmonary involvement, vertebral osteomyelitis, and epidural abscess. He was treated with a six-week course of antibiotics and surgical drainage of the abscess. This case report highlights an atypical presentation of NTS infection that is associated with high morbidity and mortality, that can be reduced with early diagnosis and appropriate treatment.
BACKGROUNDCeliac disease (CD), an immune-mediated inflammation of the small intestine, occurs in genetically predisposed individuals, and is caused by sensitivity to dietary gluten and related proteins. 1 Globally, the prevalence of celiac disease is 1.4% based on serologic test results and 0.7% based on biopsy results. 2 Celiac disease is frequently associated with extra-intestinal manifestations, including iron deficiency anemia, dermatologic eruptions, type 1 diabetes mellitus, thyroid disease, neurologic symptoms, and various connective tissue disorders, but is rarely associated with cardiomyopathy. 3-5 | CASE PRESENTATIONA 33-year-old Ethiopian woman presented to the emergency department after referral from her dentist for "looking pale." She reported a 2-month history of exertional dyspnea and fatigue. She denied chest pain, shortness of breath at rest, palpitations, or orthopnea. There was no history of abnormal bleeding or bruising, heavy menses, melena, or hematochezia. The patient denied cough, fever, abdominal pain, diarrhea, or urinary complaints. She denied any rashes or weight loss.The patient was employed as a housemaid. She had no past medical or surgical history and no previous
Investigation about hydatid cyst infection in lungs and liver of sheep and its association with Klebsiella pneumonia was done ,specimens were collected from sick and healthy sheep at different slaughter houses in Iraq Cities, each specimens which contained cystic lesions were divided to three parts , 1st part was sent to microbial laboratory ,2nd part was sent to parasitology laboratory, 3rd part was sent to histopathology laboratory . A number (100) of infected specimens lung and liver were examined grossly in order to look for any cystic lesions, as well as each specimen was examined microbiologically, and were positive for both Klebsiella pneumonia and parasitism. Histopathological examination grossly showed cystic lesions on surfaces of lungs and livers with paleness appearance, microscopically pathological lesion mainly were edematous and hemorrhagic changes inside and outside alveoli in lung, with sever destructive and necrotic with hemolytic changes in livers .Reported results' concluded that most cystic lesions' specimens were presented in lung , liver which were infected with bacteria Klebsiella pneumonia.
Celiac disease is a common immune-mediated inflammatory disease of the small intestine caused by sensitivity to gluten. It’s commonly associated with various autoimmune disease, but rarely with cardiomyopathy. Our case describes a 33 year old woman presented with exertional dyspnea and fatigue, found to have celiac disease and dilated cardiomyopathy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.