Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are rare autoimmune blistering diseases. The combination of these diseases together is very rare on the scalp. We report a 52-year-old female patient with localized painful crusted and prurient erosions and hair loss just on the scalp and no mucosal involvement. Scalp lesions had persisted about 4 years and the patient was wrongly diagnosed with psoriasis in these years. Clinical findings, as well as the results of biopsy and direct immunofluorescence, detected pemphigus vulgaris and pemphigus foliaceus also we have seen features of tufted hair folliculitis. treatment with systemic and topical corticosteroids resulted in clinical remission, with regrowth of scalp hair.
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