In order to the preparation of biodegradable, bioactive and strongly adhered coating layer to the bioinert zirconia substrate, a bioactive glass (BG) was successfully coated on the zirconia plates. To achieve this goal, the zirconia plates dipped into the 45S5 BG sol in the vacuum chamber (vacuum sol-dipping method) followed by sintering to fabricate a strongly adhered BG coating on the zirconia plates. The parameters such as surface morphology and BG coating coverage ability on the zirconia plates have been assessed before and after coating with 45S5 BG. Phase structure of the BG coating based on the X-ray diffraction (XRD) result could be indexed as Na4Ca4(Si6O18). The interfacial adhesive strength between the zirconia substrate and BG coating layer was higher than the measured adhesive strength (55±7 MPa). The viability results approved the satisfying conclusion for the offered coating method on the zirconia substrates.

The purpose of this study was to evaluate the effects of commercialized denture adhesives and mouth moisturizers using direct and indirect cell cultures for in vitro examinations with human fibroblast and epithelial cells. Denture adhesives (Faston, Poligrip Powder, New Poligrip Free, Tafugurippu Kurimu, Polident Adhesive, Tafugurippu Tomei) and mouth moisturizers (Concool Mouth Gel, Biotene Oral Balance Gel) were subjected to live and dead detection and pH level determination. The mouth moisturizers showed higher cytotoxicity effects comparing with control on every cell cultures and cells, and pH level did not show any significant differences. However, there was no correlation of type of denture adhesive or mouth moisturizer with cytotoxicity. We concluded that cytotoxicity affects human cells regardless of type of material, though some dependence was noted.