Background: Early diagnosis and proper management of a large number of chronic obstructive pulmonary disease (COPD) patients are great challenges for the Chinese health care system. Although tiered medical services have been promoted by the Chinese government since 2015, they have not been ideally implemented for COPD diagnosis and management.Methods: We designed a cross-sectional study. Eligible COPD patients (n=648) and physicians (n=161) were consecutively recruited from 8 hospitals in different tiers in East China. COPD characteristics and treatments were compared among hospitals in different tiers. Multivariate logistic regression was performed to identify risk factors associated with airflow limitation, symptoms and acute exacerbation.Results: The PFT rate at first diagnosis was 99%, 69.4% and 29.9% in teaching, second-tier and community hospitals (P<0.001). Only approximately 10.9%, 1.7% and 9.6% and 21.8%, 6.9% and 32% of COPD patients received influenza or pneumococcal vaccines (P<0.001). The proportion of patients who did not use inhaled drugs or had irregular inhalation was 2%, 24.6% and 78.8% (P <0.001). Education level (RR-1=-41.26%, P=0.007), FEV1%pred (RR-1=-2.76%, P<0.001), and influenza vaccination in the last year (RR-1=-64.53%, P=0.006) were all negatively correlated with COPD acute exacerbation (AE). COPD duration (RR-1=131.73%, P=0.009), AE (RR-1=151.39%, P<0.001), and COPD Assessment Test (CAT) scores (RR-1=3.82%, P=0.019) were all positively correlated with COPD airflow limitation severity. Conclusions: Differences exist in the diagnosis, treatment and management of COPD among different tiers of hospitals in East China. Teaching and second-tier hospitals can manage COPD patients relatively well. There are still some gaps compared with developed countries.
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