Aims:To compare the shear bond strength of sixth generation and seventh generation bonding agents to dentin.Materials and Methods:Eighty human maxillary premolars were reduced to expose flat surface of dentin and divided into four equal groups, which were bonded using following bonding agents: Sixth generation bonding agents, Adper SE Plus and Xeno III and Seventh generation bonding agents, Adper Easy One and Xeno V. Composite cylinders were then built using a plastic mould on these prepared dentinal surfaces. Samples were stored in distilled water for 24 hours and tested for shear bond strength with universal testing machine. Shear force was applied perpendicular to the long axis of composite cylinder at adhesive-tooth interface until debonding occurred. The data so obtained were tabulated and analyzed statistically using independent-samples t test and analysis of variance (ANOVA) testResults:The seventh generation adhesives showed significantly higher shear bond strength to dentin compared to sixth generation adhesives (P < 0.01). The highest value of shear bond strength was obtained from Adper Easy One system, while Adper SE Plus gave the lowest shear bond strength values.Conclusions:Seventh generation adhesives are more advantageous than sixth generation adhesives in dentin bonding as it requires less time, fewer steps, and better bond strength.

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