Collagen and elastine of the aorta were estimated in normal chickens of both sexes in cockerels, gonadectomized or treated with estradiol, and in hens treated with testosterone.
The results showed that collagen and elastine were significantly higher in males than in females. Gonadectomy in males decreased significantly the content of collagen and elastine, so that the values became similar to those observed in females. The treatment of males with estradiol lowered the collagen and elastine content to values similar to those observed in females and in gonadectomized males. The treatment of females with testosterone increased significantly the collagen and elastine content of the aorta to levels similar to those observed in males.
The survival rates of patients who complied with all the inclusion criteria for INES trials are higher compared to those that included also not registered patients. Five-year EFS and OS for INES 99.2 were 87.8 and 95.7 %, while our stage 4s population obtained 78 and 87 %. Concerning 99.3, 5-year EFS and OS were 86.7 and 95.6 %, while for stage 4 we registered 61 and 68 %. MYCN amplification had a strong impact on prognosis and therefore we consider it unacceptable that many patients were not studied for MYCN and probably inadequately treated. Ten-year survival rates were shown to decrease: EFS from 73 to 70 % and OS from 81 to 74 %, indicating a risk of late events, particularly in stage 4s. Population-based registries like European ENCCA WP 11-task 11 will possibly clarify these data.
The aging of the Spanish population has led to an increasingly greater
number of hip fractures attended by the Spanish Healthcare System in the
last years. Those patients, due to their fragility, need special
professional attention and consequently, Orthogeriatric Units (UOG) have
achieved the highest benefits.The main purpose of this research project is
to evaluate the principle variables associated to the elderly affected of
hip fracture staying in a new Orthogeriatric Unit created at the Hospital
Nuestra Señora de Candelaria in Tenerife, Spain. A descriptive study of the
elderly patients diagnosed of hip fracture staying in a conventional
Orthopedic Ward was conducted, focusing specifically in those who were
transferred to the UOG. The main items to describe were: total time of
in-hospital staying, type of hip fracture and the kind of surgery selected,
physiotherapist sessions in the conventional Orthopedic Ward, in the UOG and
in Home Hospitalization Unit (HADO) as well as the total number of patients
that needed to continue ambulatory physiotherapist sessions. As a
conclusion, early start of physiotherapist sessions inside the hospital,
completed in the UOG and/or in HADO, along with counseling and professional
assessment to families and patients, reduced a very high percentage of their
need for ambulatory ongoing rehabilitation.
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