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Introduction Orgasmic dysfunction (OD) is defined as the inability to achieve an orgasm, markedly diminished intensity of orgasmic sensations, or marked delay of orgasm during any kind of sexual stimulation. OD definition and method of diagnosis vary widely across studies. Aim The aim of this study was to identify the prevalence and risk factors that predispose Mexican women to OD. Methods A representative sample of women from Mexico City was surveyed using an online website. Women between 18 to 40 years old were selected, and the orgasm domain from the Female Sexual Function Index was used to identify OD. A cutoff point was calculated using a construct with a histogram and calculated median. A univariate and multivariate analysis was conducted to examine the relationship between potential risk factors and sexual function. Main Outcome Measures OD prevalence; significant risk factors on multivariate analysis. Results OD prevalence was 18.3%. Univariate analysis showed younger age (P = 0.01), lower degree of education (P = 0.02), single marital status (P = 0.038), and dissatisfaction with the thickness and/or size of partner's penis (P = 0.01) as significant variables related to OD. In multivariate analysis, younger age (P = 0.01) and dissatisfaction with the thickness/size of partner's penis (hazard ratio 3.04, P = 0.01) remained significant. Conclusion OD is a prevalent alteration in young women. Marital status, education, and dissatisfaction with thickness/size of partner's penis are definitely related variables.

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Este artículo debe citarse comoCabrera-Sánchez LA, Calao-Pérez MB, González-Murillo EA, Madero-Guerrero JA, Aragón-Tovar AR. Cáncer vesical de células escamosas: reporte de un caso y revisión de la bibliografía. Rev Mex Urol. 2018 nov-dic;78(6):440-46. DOI: https://doi.org/10.24245/revmexurol.v78i6.2293 Resumen ANTECEDENTES: El carcinoma de células escamosas es una variedad histológica excepcional del cáncer vesical, pues se estima en 1.6-8% de los casos.CASO CLÍNICO: Mujer de 58 años que inició con cuadro clínico de hematuria macroscópica, formadora de coágulos y anemia. La cistoscopia reportó un tumor vesical de 4 cm en la pared anterior y fondo vesical. El reporte histopatológico de la resección transuretral de vejiga fue: carcinoma urotelial de alto grado con diferenciación escamosa, invasión a la capa muscular, permeación vascular y perineural. El tratamiento consisitió en cistectomía radical y formación de conducto ileal. Cinco diás después de la cirugía se dio de alta del hospital, sin complicaciones aparentes. El reporte de patología confirmó el diagnóstico de carcinoma escamoso moderadamente diferenciado, con infiltración al tejido perivesical; la inmunohistoquímica resultó positiva para citoqueratina 5/6 y p/63. Con estos resultados se programó a la paciente para recibir tratamiento coadyuvante con radioterapia. CONCLUSIONES: El cáncer vesical es una neoplasia de reporte obligatorio, principalmente sus variedades inusuales (carcinoma de células escamosas), pues contribuye a la estadística nacional y proporciona resultados del tratamiento radical. PALABRAS CLAVE: Cáncer vesical escamoso; México.Abstract BACKGROUND: Squamous cell carcinoma of the bladder is a rare histologic variety of bladder cancer, accounting for 1.6-8% of cases. CLINICAL CASE:A 58-year-old woman presented with clot-forming gross hematuria and anemia. Cystoscopy revealed a 4 cm tumor on the anterior wall and fundus of the bladder and the histopathologic study from the transurethral resection of the bladder reported high-grade urothelial carcinoma with squamous cell differentiation, invasion of the muscle layer, and vascular and perineural permeation. Treatment was radical cystectomy plus the formation of an ileal pouch. The patient was released on postoperative day 5 with no complications. The pathology study result was moderately differentiated squamous cell carcinoma invading the perivesical tissue, confirming the previous diagnosis. Immunohistochemistry was positive for cytokeratin 5/6 and p/63. The patient was referred for adjuvant radiation therapy. CONCLUSIONS:The report of unusual types of bladder cancer (squamous cell carcinoma) is vitally important as a contribution to national statistics and to know the results of radical treatment.