Optimized Synthesis of Diamino-Triazinylmethyl Benzoates as Inhibitors of Rad6B Ubiquitin Conjugating Enzyme. -Two newly optimized routes to the target compounds (VI) are presented. The key transformation is the condensation/cyclization between substrate (I) and either dimethyloxalate or ethyl bromoacetate. -(KOTHAYER, H.; MORELLI, M.; BRAHEMI, G.; ELSHANAWANI, A. A.; ABU KULL, M. E.; EL-SABBAGH, O. I.; SHEKHAR, M. P. V.; WESTWELL*, A. D.; Tetrahedron Lett. 55 (2014) 51, 7015-7018, http://dx.
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