<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hypermelanosis of the skin. Dermoscopy is a new non-invasive tool which is used to visualise the pigment colour and distribution. This study was undertaken to explore the usefulness of dermoscope in comparison to Wood’s lamp in melasma.</span></p><p class="abstract"><strong>Methods:</strong> A total of 50 patients of melasma were examined clinically, under Wood’s lamp and with dermoscope. All the findings were recorded, described and analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> The data was compared using SPSS software and the degree of agreement between Wood’s lamp and dermoscopy was found to be substantial (K =0.833, p =<0.001)<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Dermoscopy is better tool in determining the depth of pigmentation. It gives an additional advantage to visualize the vasculature.</span></p>
<p class="abstract"><strong>Background:</strong> Melasma is an acquired hyperpigmentation of face predominantly affecting women with multiple factors like high estrogen states, genetic factors, sunlight, cosmetics & autoimmune thyroid disease implicated in its etiology. Current therapeutic modalities are beneficial for many patients but for some they may remain ineffective. The objective of the study was on clinical study of melisma and to study efficacy of 40% glycolic acid facial peels in melasma.</p><p class="abstract"><strong>Methods:</strong> Woods lamp examination was done and patients were classified as having epidermal, dermal or mixed type. 40% glycolic acid peel was carried for a period of 20-30 seconds and was left for a period of 3 minutes or till the development of erythema. The peel was terminated by dilutional effect of washing with cold water. Six peelings were done at 15 days interval.<strong></strong></p><p class="abstract"><strong>Results:</strong> In total 50 patients, 56% belong to 31-40 years.<strong> </strong>Females constitute 82%. Majority were housewives (64%). Malar distribution was most common type (90%). Family history was present in 38%. Photo aggravation was present in 56% patients. Onset of melasma was associated with pregnancy in 22%. Epidermal melasma was seen in 62%. >75% improvement in 2%, 51-75% improvement in 14% and 25-50% improvement in 40% patients. Erythema (54%) and burning sensation (56%) were common side effects.</p><p class="abstract"><strong>Conclusions:</strong> So management of melasma in our patients with superficial glycolic acid peels alone is not highly rewarding.</p>
Lichen sclerosis et atrophicus is rare chronic inflammatory dermatoses of unknown yet multifactorial etiology. The disease tends to affect the anogenital region either alone or in combination with other areas. Extragenital areas are affected in the form of depressed and atrophic, whitish macule or plaques. The lesions tend to affect the upper half of the trunk, neck and upper limbs. We are reporting a case of 45 years old female patient who presented with multiple hypopigmented to depigmented plaques with hyperpigmented border over the anterior, posterior and lateral aspect of both legs since five years associated with moderate grade itching. Dermoscopic examination shows homogenous white areas with mixed blood vessels. Histopathology examination showed features suggestive of lichen sclerosis et atrophicus. This case has been reported for its rarity and atypical presentation.
INTRODUCTION Melasma is an acquired hypermelanosis of sun exposed areas commonly seen in women, it can also occur in men. It presents as symmetrical hyperpigmented macules and patches commonly over the cheeks, nose, chin and forehead. Woods lamp is a useful device used to estimate the depth of melanin determined by light induced fluorescence. A dermoscope is a non-invasive diagnostic tool which enables a clear visualization of pigment distribution and color variation of melanin depending on its location within the skin. OBJECTIVE To classify melasma according to depth of melanin by dermoscopy and correlate woods lamp and dermoscopic findings. MATERIAL AND METHODS Analysis of concordance between woods lamp and dermoscopy in classification of melasma. 30 patients with facial melasma were examined using Woods lamp (Derma India) and Dermoscope (Dermlite DL3). On Woods lamp examination, melasma was considered epidermal when enhancement was noted, dermal when no enhancement was seen and mixed when few areas showed enhancement. On Dermoscopy, melasma was considered epidermal when regular pigment network with a brownish homogenous pigmentation was noted, dermal when irregular network with bluish grey pigmentation was noted and mixed when areas show both features. RESULTS The degree of concordance between the methods was considered good (k<0.56) by statistical analysis. CONCLUSION Dermoscopy is more suitable for examination for melasma, since it allows visualization of pigmentary components in more objective way. It also helps to understand the prognosis and management.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.