Introduction: Neonatal Sepsis is difcult to differentiate from other conditions due to non- specic clinical signs and symptoms. Inammation in
neonates shows variations in hematological parameters. Our study is to evaluate the hematological parameters and C-reactive protein estimation in
neonatal sepsis for early diagnosis.
Material And Methods: It was a cross-sectional study including 80 neonates admitted in the neonatal care unit, 40 (proven sepsis) and 40 probable
cases); blood culture being the gold standard. Hematological parameters, immature to total neutrophil ratio (I/T ratio), Absolute neutrophil count
(ANC), CRP and Blood culture were done as per standard protocols.
Results: ANC had highest sensitivity of 90% followed by I/T ratio (87.5%) and CRP (77.5%). The sensitivity and specicity for the combination of
ANC and I/T ratio was 78.3% and 83.6% respectively.
Conclusion: ANC, I/T Ratio and CRP are quick, simple and cost-effective routine laboratory tests which help in neonatal sepsis prediction and to
start proper and timely antibiotic therapy.
Renal failure is a medical condition in which the kidney fails to lter
waste products from the blood efciently. As per National Kidney
rd Foundation (NKF) in India, kidney diseases rank 3 amongst life
st threatening diseases, after cancer and heart disease, which rank 1 and
nd 2 respectively. Chronic Kidney Disease (CKD) is dened as a
progressive deterioration in nephron number and function of the
kidneys, due to different causes and there is kidney damage marked by
albuminuria and GFR less than 60 mL/min per 1.73 m2 for less than or
equal to 3 months. Kidney damage is demonstrate
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