Als Homoenolatäquivalente werden erstmals Zirconocen‐1‐aza‐1,3‐dienkomplexe in der stereoselektiven Synthese eingesetzt. Durch Insertion unsymmetrischer Ketone in die Zr‐C‐σ‐Bindung werden sterisch anspruchsvolle trisubstituierte Dihydro‐ und Tetrahydrofurane in guten Gesamtausbeuten und mit hohen Diastereoselektivitäten zugänglich (siehe unten).
As homoenolate equivalents, zirconocene-1-aza-1,3-diene complexes were used for the first time in stereoselective synthesis. By insertion of an unsymmetrical ketone in the Zr-C σ bond, sterically demanding trisubstituted dihydro- and tetrahydrofuran derivatives were prepared in good overall yields and with high diastereoselectivities (see below).
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