Background: Chronic constipation is a prevalent gastrointestinal (GI) motility disorder. To date, there is a lack of real-world evidence on the current treatment approaches and patterns in the management of chronic constipation in India.Methods: We administered a cross-sectional, physical and digital-based survey between May 2021 and November 2021 to experienced gastroenterologists from different zones of India whose practices encompass direct care of patients with chronic constipation. The questionnaire included 30 close-ended questions on qualitative aspects of constipation management, with specific focus on physicians’ experience with efficacy, tolerability and compliance of Duphalac bulk, a combination of soluble fibers and lactulose. Responses of survey participants were summarized and analyzed using descriptive statistics. All analyses were performed using SPSS 25.0.Results: The survey was completed by 195 respondents, of which, 81.5% of physicians preferred osmotic laxatives plus fibers for the management of chronic constipation. Soluble fibers are the preferred choice of physicians (84.6%) over insoluble fibers and lactulose plus soluble fibers was the most preferred in the management of constipation symptoms. The efficacy, tolerability and compliance of Duphalac® bulk were found to be highly satisfactory.Conclusions: In this survey, key practice-relevant information on the current treatment approaches related to the management of chronic constipation from Indian were garnered. The use of soluble fibers was found to be preferred over insoluble fibers, and the clinical profile of a combination formulation of soluble fibers and lactulose was found to be extremely satisfactory among the survey population.
Purpose:
This study aimed to correlate the pericoronal width surrounding impacted mandibular third molars with their histopathological findings.
Materials and Methods:
The present study included patients who were advised for extraction of impacted mandibular third molars with the pericoronal radiolucency radiographically. The CBCT scans were compared with histopathologic findings of the follicles.
Results:
Out of 70 patients evaluated histopathologically, 24 patients showed mild inflammatory changes, whereas 34 patients revealed cystic changes suggestive of a dentigerous cyst, followed by 12 patients showing evidence of calcifications in the pericoronal follicles. The dentigerous cyst was more likely to occur if the bucco-lingual width of the pericoronal radiolucency was 14.00-16.00mm, and calcifications were found to be most likely present if the buccolingual width was 12.00-14.00mm, both of which were statistically significant.
Conclusion:
CBCT can be a reliable tool in the evaluation of pericoronal follicular space, and the values in different dimensions can be an accurate predictor radiologically for the diagnosis of pathologies when compared to 2D imaging.
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