porphyrins and their copper complexes were synthesized by two different approaches using Suzuki-Miyaura cross-coupling reactions. The first , involving the formation of 5-arylthien-2yl carbaldehydes, followed by condensation with pyrrole. The second is a -direct process that involves the coupling of meso-tetra (5-bromothien-2-yl) porphyrins with the arylboronic acids. The yield of the second approach (40-50%) was higher than the first approach (28-35%). The UV-Vis absorption spectra of the synthesized porphyrins revealed bathochromic shifts when compared with the parent porphyrin. Additionally, the products showed no aggregation behaviour in solution (DCM), giving a linear correlation between absorption intensity and the concentration.
A convenient method for synthesis of symmetrical diarylureas from carbamtes is reported. The diarylureas were obtained in excellent yield when carbamates were boiled at reflux in dry benzene in the presence of sodium hydride as a catalyst and 18-Crown-6 ( 18 C6 ) as a co-catalyst. A plausible mechanism explains the formation of 1,3-diarylureas from carbamates in the presence of basic catalyst is reported. The chemical structure of the diarylureas was confirmed by spectroscopic techniques and compared with an authentic sample prepared using previously reported methods.
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