Autologous platelet rich plasma injection and platelet rich fibrin glue interposition offer a safe, effective and novel minimally invasive approach for the treatment of vesicovaginal fistula which obviate the need for open surgery. We propose calling this technique the Hamidi-Shirvan method.

Cell therapy consisting of intrasphincteric and submucosal injections of autologous TNCs along with platelets in SUI patients is a feasible and safe procedure. The results point out those subjects cured or with marked improvement after 6 months F/U.

BackgroundUrinary stone incidence in pregnancy has been reported in a wide range, from 1 in 200 to 1 in 2000 cases.ObjectivesThe aim of this study was to investigate the efficacy and safety of ureteroscopic treatment and its results and complications for pregnant women with urinary stones.Patients and MethodsFrom 2003 till 2011, 113 pregnant patients with symptomatic urolithiasis were admitted to the urology emergency clinic at Imam Reza hospital. All patients were initially treated conservatively, resulting in spontaneous passage of the calculi in 69 patients. Forty-four patients with symptomatic urolithiasis were included in the study. Post-operative follow ups, including maternal and fetal health was performed by a gynecologist consult fetal heart rate assessment and urine analysis and culture and renal and urethral ultrasonography.ResultsThe mean age of the patients was 23 years ± 2 (19-34) and the mean gestational age was 24 ± 3 weeks. The overall and pneumatic lithotripsy success rate was 100%. All patients from the interventional group delivered at term with no fetal or maternal complications. There was no morbidity during and after the operation.ConclusionsIn conditions, medical management of urinary stones and consequent renal colic in pregnant women cannot improve patients’ symptoms, choosing of a surgical method like setting of a DJ catheter or URS and pneumatic lithotripsy can be a safe and effective way for the health of both the mother and fetus. Of course, more research is needed to establish this approach as the standard method in pregnancy urinary stones.

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Background: Human T-lymphocyte virus type-1 (HTLV-1) infection and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are endemic in the northeastern population of Iran. Urologic manifestations of the syndrome are different in various stages of HAM and should be evaluated via urodynamic study. The northeastern region of Iran is among the endemic areas; therefore, a comprehensive study is needed to investigate the clinical symptoms and urodynamic findings of these patients. Methods: In this study, we examined the clinical features and urodynamic findings of 50 HAM/TSP patients who referred to the urology clinic of Imam Reza Hospital in Mashhad. Data were collected using checklists and analyzed by SPSS software. The significance level of 0.05 was used in all statistical tests.Results: Among 50 patients, 27 (54%) were female. The mean age was 57.56 ± 11 years. The most common clinical findings in patients were urinary frequency (88%), followed by urgency (86%). In addition, the most common urodynamic finding was detrusor overactivity (DO; 78%). Among the studied patients, 62% had pain in the low back or lower extremities, 10% had detrusor sphincter dyssynergia (DSD), 66% had a kind of sensory abnormality, 46% had urinary incontinence, 4% had retention, and 34% had no clinical signs. Regarding neurological symptoms, 36% had rigidity and 28% had an abnormal gait. There was a significant relationship between abnormal gait and DO, DSD, urodynamic incontinence, and decreased urinary compliance (P = 0.01, 0.02, 0.009, and 0.002, respectively). Conclusions: We found that neurologic symptoms and lower urinary tract symptoms (LUTS) do not always synchronize and LUTS may be related to neurologic symptoms. Therefore, urinary and urodynamic evaluations must be performed in the first step for HAM/TSP patients. Among LUTS, only was urinary urgency related to urodynamic findings. Neurologic symptoms were significantly associated with DSD and thus, they can alarm for upper urinary tract damage.