A novel Ru(iii) complexes were synthesized and characterized. Their stabilities were discussed in terms of aqueous and MeCN solutions. Antimicrobial properties of complexes studied were characterized against reference strains of bacteria and yeast.
The physicochemical characterizations of PAOX were obtained both in solid-state and solution, and its two anti-conformers were observed in the X-ray. Its antimicrobial properties were tested against reference strains of bacteria and yeast.
Background:
Analytical chemistry and biotechnology as an interdisciplinary
fields of science have been developed during many years and are experiencing significant
growth, to cover a wide range of microorganisms separation techniques and methods, utilized
for medical therapeutic and diagnostic purposes. Currently scientific reports contribute
by introducing electrophoretical and immunological methods and formation of devices
applied in food protection (avoiding epidemiological diseases) and healthcare (safety ensuring
in hospitals).
Methods:
Electrophoretic as well as nucleic-acid-based or specific immunological methods
have contributed tremendously to the advance of analyses in recent three decades,
particularly in relation to bacteria, viruses and fungi identifications, especially in medical
in vitro diagnostics, as well as in environmental or food protection.
Results:
The paper presents the pathogen detection competitiveness of these methods
against conventional ones, which are still too time consuming and also labor intensive.
The review is presented in several parts following the current trends in improved pathogens
separation and detection methods and their subsequent use in medical diagnosis.
Discussion:
Part one, consists of elemental knowledge about microorganisms as an introduction
to their characterization: descriptions of divisions, sizes, membranes (cells) components.
Second section includes the development, new technological and practical solution descriptions
used in electrophoretical procedures during microbes analyses, with special attention
paid to bio-samples analyses like blood, urine, lymph or wastewater. Third part covers biomolecular
areas that have created a basis needed to identify the progress, limitations and challenges
of nucleic-acid-based and immunological techniques discussed to emphasize the advantages
of new separative techniques in selective fractionating of microorganisms.
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