The currently developing devastating pandemic of the coronavirus disease 2019 (COVID-19) has took over the global attention. Meanwhile, another virus with high potentiality to grow into a global pandemic has emerged in China, where human infections of the strain genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus had been reported. However, fortunately human-to-human transmission was not detected yet but we need to keep an eye out for such potential scenario particularly that by the time we fully understand the virus transmission it might be too late to contain it and prevent a second global crisis. Health systems are collapsing under the current COVID-19 pandemic, nevertheless, we need to prepare for worst situation of having two pandemics side-by-side which would be a disastrous threatening the entire humanity. A better international commitment for collaboration, one health and early detection and response system need to be on place worldwide.
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