No abstract
The purpose of the study is to estimate of probable predictors for the probable predictors of knee joint osteoarthritis progression in X-ray negative stage based on ultrasound examination. The sixty five patients with X-ray negative gonarthritis were selected into the study. Both X-ray and ultrasound examinations were performed for each of the patients (before the study and since one year). The authors determined degeneration of the medial meniscus and articular surfaces roughness had the most degree of sensitivity (91%), and cartilage thickness of medial joint parts (86%). The degenerative changes of the posterior cruciate ligament had the lowest sensitivity (42%), and degeneration in the lateral meniscus (47%). During the regression analysis only two quality indicator such as cartilage thickness of the medial parts, and articular surfaces brought significant contribution to the risk prediction of the osteoarthritis progression (odds ratio=22.7 and 71.4; p=0.018 and 0.002, respectively). The degeneration in the anterior cruciate ligament was not significant for the model (odds ratio= 26,3; p=0.05).
Aim: a comparison of the mifepristone in different doses effectiveness to prepare the cervix of uterus for delivery with its unsatisfactory "ripening" in 37-41 weeks pregnancy. Material and Subjects: the object of a continuous prospective study were 205 women who delivered babies in Maternity hospital №1 of town Tula for 2010-2011 yy with unsatisfactory "ripening" of the cervix at term pregnancy. Study groups was formed by a dosage of using the medical drug to prepare the cervix of uterus for delivery. Group IA was consisted of 177 pregnant women who received mifepristone peroral by a standard scheme, the group IB - 28 pregnant women who received mifepristone by the minimized scheme of the drug. The cervix of uterus readiness for childbirth was assessed by vaginal examination in accordance with the scale E.H. Bishop. Results: after medical treating by mifepristone "not ready enough" cervix of uterus were received the same results in both groups. The cervix of uterus condition improved to full readiness to 82,7% in IA and 83,3% cases in the IB group (OR=0,96; 95% CI of 0,23 to 4,0). In patients who initially had an "unripe" cervix of uterus after administration of mifepristone was noted significant improvement in her condition, - in group IA 66,4% of women had "ripe" cervix, in 24,8% were "not ripe enough" and 8,8% remained "unripe". In the IB group were obtained almost similar results: 60,0%, 30,0% and 10,0% respectively (p>0,05). It was´t found significant differences between groups in aspects of the delivery and the health status of newborns. Conclusion: the efficacy of mifepristone using in a dose of 200 mg 2 times with an interval of 24 hours to prepare the cervix of uterus for delivery is similar with the use of this drug in a dose of 100 mg 2 times with an interval of 24 hours for "not ripe enough" and acceptable for "unripe" cervix condition at 37-41 weeks of gestation. Pregnant women with a necessary the cervix of uterus preparation for to optimize hospital care perhaps the use of mifepristone in the outpatient setting for 3 days prior to hospitalization for childbirth.
In the article results of use of experimental-statistical models "modifying additives, dispersible fibers – property" for study of physico-mechanical characteristics of modified fiber-reinforced fine-grained concretes are shown. Advantages of application of the models in this class are displayed. 7 triangular Gibbs-Roseboom’s diagrams fixed in 7 points of bearing triangle with the isolines of maximums of the investigated properties, built with the use of the program Statistica 10.0.1011, and graphic dependences of its are given.
Тема общественного контроля имеет большой исследовательский потенциал и поэтому часто становится предметом научных исследований. Вместе с тем проблема общественного контроля за соблюдением открытости информации о деятельности публичной власти мало изучена и недостаточно научно разработана. При этом обеспечение открытости информации о деятельности публичной власти является важным направлением общественного контроля. Проблема открытости публичной власти рассматривается в статье исходя из постулата, что обеспечение открытости информации-это, прежде всего, вопрос доверия общества и его граждан к органам власти. Отмечается, что открытость органов публичной власти позволяет создавать среду открытого диалога с гражданами и таким образом обеспечивать высокий уровень доверия со стороны граждан, привлекая широкое внимание к вопросам государственного управления и вовлекая граждан в совместный поиск решений проблем. Автором была предпринята попытка проанализировать и оценить состояние, а также перспективы развития общественного контроля за соблюдением открытости публичной власти. Кроме того, рассмотрены возможности и способы взаимодействия органов публичной власти с гражданами, организациями в развитии механизмов общественного контроля. Методологическую основу исследования составляет совокупность методов научного познания, среди которых ведущее место занимает диалектический метод. Использованы общефилософские, общенаучные и специально-юридические методы исследования. Особое внимание уделялось сравнительному и системному методам исследования. Отмечается, что информационная открытость деятельности органов публичной власти способствует реализации механизмов участия гражданского общества и его институтов в общественном контроле. В связи с этим необходимо продолжить развивать правовые возможности доступа к информации о деятельности публичной власти для граждан и организаций, а также создавать условия информационной открытости и доступности сведений о деятельности публичной власти. Ключевые слова: общественный контроль, публичная власть, открытость, информация, деятельность, общество, управление, государство, законодательство.
Osteoarthritis is a group of different diseases with similar manifestations, which are based on the defeat of all of the joint parts (primarily of cartilage and subchondral bone, synovium, ligaments capsule) and periarticular muscles. The purpose of the study is to characterize cartilage structure and periarticular changes of tissue by means of ultrasound and magnetic resonance imaging without X-ray verification of osteoarthritis. Thirty eight patients with X-ray negative stage of osteoarthritis were ex-amined by ultrasound and magnetic resonance imaging. Pathological changes were detected in majority of the patients. The edema of soft tissue, exudate, changes in ligaments, deformation of joint surface were revealed in 71-74%, 11-37%, 76-68% and 58-68% of patients respectively. In general, pathological changes tended to be revealed on magnetic resonance imaging more frequently comparatively to ultrasound examination. Both ultrasound examination and magnetic resonance imaging are comprehensive methods for early detection of knee osteoarthritis. The prognostic value of the changes is to be evaluated.
A retrospective analysis was carried out on the basis of epidemiological indicators such as prevalence and incidence for diseases of the musculo-skeletal system and osteoarthritis among residents of Arkhangelsk region and Krasnodar region. The incidence trends to increasing for diseases of bones and joints during the period of 2000-2012 years showed (in the Russian Federation for 13 years of growth was 8%, in the Arkhangelsk Region - 31%, and the Krasnodar Region- 142%). The similar results were obtained in studies for osteoarthritis (in Russia increase by 55% over 13 years for 41% of the Arkhangelsk Region, Krasnodar Region - 46%). Maximum growth indicator prevalence of diseases of the musculo-skeletal system was observed in the Krasnodar region and was 69% and in the Arkhangelsk region - 30%, in Russia on average increase was 26%. For thirteen years also marked increase in the prevalence of osteoarthritis in Russia as a whole and in the Arkhangelsk region and the Krasnodar region. Environmental and climate and geographical features of investigated regions can cause the detected differences.
In the article the theoretical bases of the program approach of the development of technical infrastructure are revealed. This direction is based on receiving a certain outcome in solving the problem. Target orientation involves setting the objectives for which the program actions are provided. Proposals on the development of the program in the form of a draft concept of additional regional program will be based on the indicative rates.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.