Introduction: The most common form of osteoarthritis (OA) is osteoarthritis of the knee. Conservative treatment of OA is effective only in stages I and II of the disease. Meanwhile, increasing incidence of knee osteoarthritis and lowering ages of the disease onset makes high tibial osteotomy (HTO) more and more vital, allowing to extend the function of the own knee joint and to postpone or completely avoid total knee replacement (TKR). The aim of the study was to assess the effectiveness of НTO at 2-3 stages of knee osteoarthritis and to investigate the influence of age, body mass index (BMI) and correction angle on the nearest result of the operation. Materials and methods: during the period from 2003 to 2016, 35 HTOs were performed in 32 patients. The ratio of men to women was 2:1. The mean age was 59.0±13.1 years, a BMI of 29.04±3.57kg/m² and a correction angle of 12.5±2.78°. A visual analogue scale (VAS) was used to assess the pain severity. The Knee Society Score (KSS) was applied to assess the functional and objective state of the knee joint. The stage of the degenerative process was evaluated according to the X-ray classification of Kellgren-Lawrence. Results: The HTO was effective in patients with both 2nd and 3rd stages of knee osteoarthritis. One year after the operation, a significant reduction in VAS scores (from 72.27±11.79 mm to 7.72±6.62mm) and an improvement in functional and objective KSS scores (from 43.66±11.5mm and 54, 39±11.77mm to 86.51±10.86mm and 81.93±6.65mm) were observed. We obtained the following results of the HTO: excellent (36.4%), good (57.6%) and satisfactory (6%). The X-ray signs of progression of the disease were not revealed one year after the operation. The connection of BMI with the nearest result of the operation was revealed. (Spearman coefficient=-0.34 at p <0.05). Conclusion: HTO is more effective at the 2-nd stage of osteoarthritis of the knee compared with the third stage. Age and angle of correction do not affect the nearest result, while increased values of body mass index are associated with worse result and complications.
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