No abstract

Accurate forecasts of ocean waves energy can not only reduce costs for investment, but it is also essential for the management and operation of electrical power. This paper presents an innovative approach based on long short-term memory (LSTM) to predict the power generation of an economical wave energy converter named “Searaser”. The data for analysis is provided by collecting the experimental data from another study and the exerted data from a numerical simulation of Searaser. The simulation is performed with Flow-3D software, which has high capability in analyzing fluid–solid interactions. The lack of relation between wind speed and output power in previous studies needs to be investigated in this field. Therefore, in this study, wind speed and output power are related with an LSTM method. Moreover, it can be inferred that the LSTM network is able to predict power in terms of height more accurately and faster than the numerical solution in a field of predicting. The network output figures show a great agreement, and the root mean square is 0.49 in the mean value related to the accuracy of the LSTM method. Furthermore, the mathematical relation between the generated power and wave height was introduced by curve fitting of the power function to the result of the LSTM method.

Local injection of botulinum toxin-A is an accepted treatment for hyperhidrosis. We report 2 cases of primary hyperhidrosis who developed iatrogenic botulism after the therapeutic dose of onabotulinumtoxinA (Botox). This case report highlights the necessity of clinicians having sufficient information of potentially adverse effects, optimal dose, and correct preparation and injection of botulinum toxin-A.

Introduction: The comparative value and suitability of outcome measures are uncertain in chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: We studied 35 patients with CIDP using the Overall Neuropathy Limitation Scale (ONLS), the inflammatory Rasch-built Overall Disability Scale (I-RODS), and the Medical Research Council Sum Score (MRCSS).Results: Significant associations were determined between initial deficit and ONLS score (P = .002) and MRCSS improvement (P = .001) but not I-RODS score. A strong inverse correlation was observed between disease duration and I-RODS score (P = .002) but not ONLS/MRCSS improvement. A strong association was observed between age ≤ 40 years and I-RODS score (P = .001) but not ONLS/MRCSS improvement. When minimum important differences were used, ONLS and I-RODS sensitivities were comparable (P = .19). Discussion: Overall Neuropathy Limitation Scale and I-RODS are equally sensitive in identifying change. Ease of administration, better ability to detect improvement in severe disease, and greater amplitude responses throughout the disease and in older patients favor the ONLS. The I-RODS appears more useful in early disease/younger patients. K E Y W O R D S chronic inflammatory demyelinating polyneuropathy, disability, minimal important difference, outcome measures, sensitivity, suitability, value

This study was designed to evaluate the efficacy of gabapentin (GBP) in the treatment of SUNCT syndrome on a relatively large sample of Persian patients. Eight patients with SUNCT syndrome underwent a 4-week, open-label, daily treatment of 600-900 mg GBP. The frequency, intensity and duration of attacks were compared before and after the trial. After 4 weeks of treatment, intensity, duration and frequency of headaches were significantly (P < 0.05) reduced. In addition, five patients (62.5%) were completely relieved from headaches, and in the other three patients the mean intensity, frequency and duration of headaches were decreased notably. In this study, GBP was well tolerated and no unfavourable side-effects were reported. After the end of the trial all patients continued the medication, and after 3 months none reported undesired side-effects or return of the headaches to the pre-treatment status. Our patients had a significant response to GBP, and considering other case reports on the effectiveness of GBP in the treatment of SUNCT syndrome, we propose that, taking into account the good side-effect profile and lack of interactions of GBP, this drug could be considered as an option for the treatment of SUNCT.