Introduction. To evaluate the efficacy and maintenance of extracorporeal shockwave therapy (ESWT) in sub-acute and chronic post-stroke spasticity patients in the Suez Canal region. Methods. An interrupted time series study was conducted; 82 patients were recruited in accordance with the defined inclusion and exclusion criteria. They were divided into 2 subgroups depending on the stroke duration: a sub-acute group (35 patients) and a chronic group (47 patients). ESWT was applied over knee and ankle flexor muscle belly with the following setup parameters: energy: 0.068-0.093 mJ/mm; frequency: 5 Hz; number of shots: 1500. Modified Ashworth score, clonus score, 3-minute walk test, range of motion angle of both knee and ankle joint, and Fugl-Meyer Assessment were established at baseline, after the 1 st session, and at the 1 st , 4 th , and 8 th week for the 2 groups. Results. Regarding the sub-acute group, there was a statistically significant improvement in the modified Ashworth score, clonus score, 3-minute walk test, and range of motion angle of both knee and ankle joint after the 1 st session and after the 1 st week of intervention. The differences were not statistically significant after 4 th or 8 th week. The chronic group showed no statistically significant improvement after the 1 st session or in the 1 st , 4 th , or 8 th week assessment. Conclusions. ESWT was more effective in treatment of spasticity in patients with sub-acute stroke compared with those with chronic stroke.
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