Objectives: to compare the mechanical, pharmacological or combination of both in induction of labour. Methods: This comparative observational study was conducted in Department of Obs and Gynae, Lady Reading Hospital, from January 2019 to December 2019. In this study all women presenting to labor room with singleton pregnancy and gestational age > 37 weeks and admitted for induction of labor were included. All those women with multiple pregnancies, premature rupture of membrane, malpresentation, and prior Cesareans section were excluded. Total 300 patients were included in the study period, Patients were divided into 4 groups, Group A (mechanical methods), Group B (prostaglandin E2), Group C (mechanical + PGE2), Group D (misoprostol). Data were analyzed using IBM SPSS Statistics for Windows, Version 23.0 (IBM Corp., Armonk, NY). Results: In this study 300 patients were included, in mean age of 24.54±12 years, with age range of 16- 40 years. Majority were Primi gravida (167 (55.7%), and 99.7 had poor bishop score. Indication for induction of 109(36.3%) was due to eclampsia / pre-eclampsia, followed by postdate pregnancy 98(32.7%). In majority of cases 123(41%) time from induction to labour was 6-12 hours. prostaglandin group showed good success rate in term of normal vaginal delivery and low adverse effects and good maternal and neonatal outcomes, followed by misoprostol, lowest success rate was recorded in mechanical only group . (p<0.001) Conclusion: Our study concludes that among different methods available for induction of labour, PGE2 is safe, effective and have goof maternal and fetal outcomes Keywords: induction, labour, PGE2, misoprostol
Objectives: To look at the manifestation of maternal vaginal colonization of Group B Streptococcus in pre-term premature rupture of membranes.Methods and materials: This cross sectional study was conducted at Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar from November 02 ,2020 to May 02, 2021. By using chi square test, Group B streptococcus (GBS ) was stratifi ed among age, gravidy, parity, BMI and booking status to see the eff ect modifi cation value ≤ 0.05 was taken as significant. Those co comorbidities that aff ect the results were excluded. All data was entered, processed, and analyzed on SPSS version 21.0.Results: Out of total 126 patients, mostly in 15-25 Years of age [04(3.17%),P value,0.889] were reported as compare to 26-35 Years of age 03(2.38%) and 0.79% years among 36-45 Years. Simailrly the frequency of Group B streptococcus (GBS) was prevalent among 15-20 kg/m2 category [04(3.17%),P value,0.083] as compare to 21-25 kg/m2 02(01.58%) and 26-30 kg/m2 having 02(01.58%)Conclusion: The gastrointentinal and vaginal epithelium of healthy women colonized by Group B Streptococcus(GBS) pose a greater risk of serious pathologies in the susceptible infant by a transmission during parturition or ascending intrauterine infection. The incidence of early-onset GBS sepsis has decreased as a result of universal screening and intra partum antibiotic prophylaxis.
Objectives: To determine the frequency of near-miss among patients admitted during pregnancy till postpartum period.Materials and Methods: This cross-sectional study was conducted in Gynecology & Obstetrics Unit (B) of Lady Reading Hospital, Peshawar from 9/12/2019 to 9/6/2020. All women between age 15-48 years during pregnancy till 42 days after the end of pregnancy, admitted in the ward were included while a pregnant lady with complication not associated with pregnancy were excluded. Data on complications, mode of delivery, age and parity were taken from registers maintained in labor room, obstetrical ward and intensive care unit. Effect modifiers like age, gestational age. parity, gravida and causes were controlled through stratifications by using chi square test while P-value < 0.05 was taken as significant.Results: Out of total of 611 women were observed in which mean age was 29 ± 10.91 years. About 238(39%) patients were observed for primi para while 373(61%) patients were multi para. Similarly, 226(37%) patients were primi gravida while most of the patients were 385(63%) were multi gravida. Only 31(5%) patients had shock while 12(2%) patients had fits and very little number of 6(1%) patients had proteinuria. More over 8% patients had near miss while 92% patients didn’t had near miss.Conclusion: Our study concludes that the frequency of near-miss was 8% among patients admitted during pregnancy till postpartum period.
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